4-((2,5-Dichlorophenyl)thio)-6-(methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine CAS 478247-57-3
| CAS No. | 478247-57-3 |
| Molecular Formula | C18H12Cl2N4S2 |
| Molecular Weight | 419.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-((2,5-Dichlorophenyl)thio)-6-(methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 478247-57-3), a certified reference material (molecular formula C18H12Cl2N4S2, MW 419.35 g/mol) for analytical method development and quality control.
The molecular framework of 4-((2,5-Dichlorophenyl)thio)-6-(methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (C18H12Cl2N4S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12Cl2N4S2 |
| Molecular Weight | 419.35 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Dichlorophenyl Standards
- {2-[(2,4-dichlorophenyl)sulfanyl]pyridin-3-yl}methyl N-(2-methylphenyl)carbamate (CAS 339278-54-5)
- N-(2,4-Dichlorophenyl)-4-hydroxy-2-oxo-1-pentyl-1,2-dihydroquinoline-3-carboxamide (CAS 303093-26-7)
- (3Z)-3-{[(3-{[(2,6-dichlorophenyl)methyl]sulfanyl}-1H-1,2,4-triazol-5-yl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one (CAS 339022-11-6)
- 7-[(3,4-Dichlorophenyl)methyl]-8-(3,5-dimethyl-1H-pyrazol-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione (CAS 1019100-13-0)
- (2Z)-1-(2,4-Dichlorophenyl)-3-[(5-iodopyridin-2-yl)amino]prop-2-en-1-one (CAS 338401-08-4)
- 4-(3-(3,5-Dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzamide (CAS 1095275-13-0)
- 1-(2,4-Dichlorophenyl)-4-methyl-5-(4-nitrophenyl)-1H-pyrazole-3-carboxylic Acid Ethyl Ester (CAS 221385-24-6)
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-6-(4-fluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338403-80-8)
Recommended Standards
- 2-Phenyl-2-(3-(3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)propanamido)acetic acid (CAS 874374-65-9)
- 4-Amino-5-benzoyl-2-((2,4-dichlorobenzyl)thio)thiophene-3-carbonitrile (CAS 478081-52-6)
- 2-(Benzylthio)-4-(2,4-dichlorophenoxy)thieno[3,2-d]pyrimidine (CAS 339018-97-2)
- 4-Amino-5-benzoyl-2-{[(3,4-dichlorophenyl)methyl]sulfanyl}thiophene-3-carbonitrile (CAS 478081-53-7)
- 2,4-Dibromo-5-fluoro-1H-benzo[d]imidazole (CAS 1388026-23-0)
- 2-Cyclopentyl-5-hydroxy-6,7-dimethyl-2,3-dihydro-1H-inden-1-one (CAS 41715-84-8)
- WAY 267464 Dihydrochloride (CAS 1432043-31-6)
- 2,4-Dibromo-6-chloroaniline (CAS 874-18-0)
- Eldecalcitol Impurity 83 (CAS CATO-C4X-214083)
- 2-(3-Bromobenzoyl)-6-methoxypyridine (CAS 1187164-97-1)
- 2-Chloro-4-(1H-indol-3-yl)pyrimidine-5-carbonitrile (CAS 2306263-35-2)
- 2-(4-Methyl-6-(methylamino)pyridin-3-yl)piperidine-1-carbaldehyde (CAS 1352492-89-7)
- 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-3H-1,3-benzodiazole (CAS 2284623-82-9)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
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