Ethyl 4-(4-{2-[(2,4-dichlorophenyl)methyl]-3-ethoxy-3-oxopropanoyl}-1H-1,2,3-triazol-1-yl)benzoate CAS 478248-77-0
| CAS No. | 478248-77-0 |
| Molecular Formula | C23H21Cl2N3O5 |
| Molecular Weight | 490.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 4-(4-{2-[(2,4-dichlorophenyl)methyl]-3-ethoxy-3-oxopropanoyl}-1H-1,2,3-triazol-1-yl)benzoate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ethyl 4-(4-{2-[(2,4-dichlorophenyl)methyl]-3-ethoxy-3-oxopropanoyl}-1H-1,2,3-triazol-1-yl)benzoate (CAS 478248-77-0), a certified reference material (molecular formula C23H21Cl2N3O5, MW 490.34 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 4-(4-{2-[(2,4-dichlorophenyl)methyl]-3-ethoxy-3-oxopropanoyl}-1H-1,2,3-triazol-1-yl)benzoate (C23H21Cl2N3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 4-(4-{2-[(2,4-dichlorophenyl)methyl]-3-ethoxy-3-oxopropanoyl}-1H-1,2,3-triazol-1-yl)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H21Cl2N3O5 |
| Molecular Weight | 490.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 5-(3,4-Dichlorophenyl)-4-(4-ethoxybenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 371211-75-5)
- (2E)-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}-3-[(4-phenoxyphenyl)amino]prop-2-en-1-one (CAS 478040-03-8)
- 6-(((2,6-Dichlorophenyl)thio)methyl)-N-methyl-2-((3-(trifluoromethyl)benzyl)thio)pyrimidin-4-amine (CAS 341965-28-4)
- 2-(2,4-Dichlorophenyl)-3-(4-(2,4-dichlorophenyl)thiazol-2-yl)-5-methylthiazolidin-4-one (CAS 866048-99-9)
- (1E)-1-[(2,4-Dichlorophenyl)amino]-2-[(2,4-dichlorophenyl)carbamoyl]-2-[(1E)-(methoxyimino)methyl]eth-1-en-1-yl acetate (CAS 338964-98-0)
- (2E)-2-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]prop-2-enenitrile (CAS 338978-48-6)
- Ethyl 5-(3,4-dichlorophenyl)-2-(4-(4-nitrophenyl)piperazin-1-yl)-1H-pyrrole-3-carboxylate (CAS 338406-41-0)
- 4-(2,4-Dichlorophenyl)-2-(4-methylpiperazin-1-yl)-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 303984-86-3)
Recommended Standards
- 11-(Perfluoro-n-hexyl)undecanol (CAS 134052-01-0)
- N'-(2,5-bis(2,2,2-trifluoroethoxy)benzoyl)-4-fluorobenzenesulfonohydrazide (CAS 477863-99-3)
- N-(4-(7-(Diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)phenyl)-2-iodoacetamide (CAS 76877-34-4)
- 2,7-Bis(2,6-difluorophenyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone (CAS 1333488-67-7)
- 3-Chloro-6-(difluoromethoxy)pyridazine (CAS 1084812-45-2)
- Ubrogepant N-Oxide 2 (CAS CATO-C4X-34027)
- 1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxamide (CAS 6433-99-4)
- Tert-butyl (3R,4S)-4-amino-3-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate (CAS 1903838-57-2)
- N-propylpicolinamide (CAS 229646-01-9)
- 7-Chloro-1-methyl-5-nitro-1H-benzo[d]imidazole (CAS 1287218-23-8)
- (E)-N,N-Dimethyl-4-(2-(pyridin-4-yl)vinyl)aniline (CAS 68971-01-7)
- (6-Benzyl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)methanamine (CAS 601515-69-9)
- Benzo(C)Phenanthrene (CAS 195-19-7)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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