1-[(4-Chlorophenyl)methyl]-1-(3,3,3-trifluoro-2-hydroxypropyl)-3-[3-(trifluoromethyl)phenyl]urea CAS 478248-81-6
| CAS No. | 478248-81-6 |
| Molecular Formula | C18H15ClF6N2O2 |
| Molecular Weight | 440.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 440.77 g/mol gives 1-[(4-Chlorophenyl)methyl]-1-(3,3,3-trifluoro-2-hydroxypropyl)-3-[3-(trifluoromethyl)phenyl]urea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-[(4-Chlorophenyl)methyl]-1-(3,3,3-trifluoro-2-hydroxypropyl)-3-[3-(trifluoromethyl)phenyl]urea (CAS 478248-81-6), molecular formula C18H15ClF6N2O2 and molecular weight 440.77 g/mol, is a CATO reference standard with documented purity and traceability.
1-[(4-Chlorophenyl)methyl]-1-(3,3,3-trifluoro-2-hydroxypropyl)-3-[3-(trifluoromethyl)phenyl]urea (C18H15ClF6N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[(4-Chlorophenyl)methyl]-1-(3,3,3-trifluoro-2-hydroxypropyl)-3-[3-(trifluoromethyl)phenyl]urea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15ClF6N2O2 |
| Molecular Weight | 440.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 1-[(4-Chlorophenyl)sulfanyl]-4-[(2,5-dichlorophenoxy)methyl]-2-nitrobenzene (CAS 477869-50-4)
- 3-(4-Chlorophenyl)-7-(5-(2,4-dichlorophenyl)furan-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 439108-97-1)
- (4Z)-4-[(4-Chlorophenyl)methylidene]-1-(4-fluorophenyl)-2-[(3,4,4-trifluorobut-3-en-1-yl)sulfanyl]-4,5-dihydro-1H-imidazol-5-one (CAS 477886-74-1)
- 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(2,4-difluorophenyl)acetamide (CAS 338957-30-5)
- 2-(2-(4-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(2,4-difluorophenyl)acetamide (CAS 338957-20-3)
- Methyl 3-((7-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)-4-methoxybenzoate (CAS 1105223-62-8)
- Methyl 3-((7-(3-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)-4-methoxybenzoate (CAS 1105238-47-8)
- (4-(7-(4-Chlorophenyl)-4-hydroxythieno[3,2-d]pyrimidin-2-yl)piperazin-1-yl)(furan-2-yl)methanone (CAS 1226446-87-2)
Recommended Standards
- Delafloxacin (CAS 189279-58-1)
- 6-[(4-Chlorobenzenesulfinyl)methyl]-N-[(2,4-dichlorophenyl)methyl]-2-methylpyrimidin-4-amine (CAS 338960-33-1)
- elafloxacin Impurity 7 (CAS CATO-C4X-26377)
- JNJ-54175446, >98% (HPLC) (CAS 1627902-21-9)
- 7-Fluoro-3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazole-5-sulfonyl chloride (CAS 2387599-33-7)
- 4-Bromo-5-methylbenzene-1,2-diamine (CAS 102169-44-8)
- 3-Iodobenzyl Bromide (CAS 49617-83-6)
- 2-(Methylthio)-3-nitropyridine (CAS 22746-79-8)
- Ethyl 4-chloro-3-formylbenzo[b]thiophene-2-carboxylate (CAS 2585607-56-1)
- 1-Chloro-3-propoxy-5-(trifluoromethyl)benzene (CAS 1881330-65-9)
- 2-{[(4-ethoxyphenyl)sulfonyl]amino}-4,5-dimethoxybenzoic acid (CAS 764696-97-1)
- 6-Bromo-2,2-dimethyl-2H-chromene-5,8-dione (CAS 557757-34-3)
- 3-Bromo-1-methyl-1H-1,2,4-triazol-5-amine (CAS 1365957-74-9)
- Neuropeptide Y, porcine (CAS 82785-45-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com