4-((2-Chloro-3-phenylallylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione CAS 478255-88-8
| CAS No. | 478255-88-8 |
| Molecular Formula | C18H15ClN4S |
| Molecular Weight | 354.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-((2-Chloro-3-phenylallylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-((2-Chloro-3-phenylallylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-88-8) is a high-purity analytical reference standard with the molecular formula C18H15ClN4S and a molecular weight of 354.86 g/mol.
Based on its molecular formula C18H15ClN4S, 4-((2-Chloro-3-phenylallylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 354.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H15ClN4S |
| Molecular Weight | 354.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-N-(2-methoxyethyl)-2-methyl-N-(pyridin-4-ylmethyl)benzenesulfonamide (CAS 1286718-29-3)
- 2-Chloro-6-(4-morpholinylcarbonyl)-N-(1,1,3,3-tetramethylbutyl)-4-pyrimidinamine (CAS 1365838-65-8)
- 2-(4-(3-Chloro-4-methoxyphenyl)-2-(diethylamino)thiazol-5-yl)acetic acid (CAS 1443287-98-6)
- (E)-3-(3-chloro-4-methoxyphenyl)-1-(4-cyclohexylphenyl)prop-2-en-1-one (CAS 861207-62-7)
- 2-((6-Chloro-1-phenylisoquinolin-3-yl)oxy)-N,N-diethylethanamine (CAS 89707-28-8)
- 2-Chloro-N-(4-(p-tolylthio)phenyl)nicotinamide (CAS 339096-30-9)
- 6-Chloro-2-(2-(phenylthio)pyridin-3-yl)benzo[d]thiazole (CAS 400075-94-7)
- 2-Chloro-3,4-bis(pivaloyloxy)acetophenone (CAS 185448-73-1)
Recommended Standards
- 4-(((5-(2-Chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)methyl)benzonitrile (CAS 5302-36-3)
- 6-((6-Chloropyridin-3-yl)methyl)-5,7-dimethyl-3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidine (CAS 866040-38-2)
- 3-(3-Chlorophenyl)-4-((2-methyl-3-phenylallylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-05-9)
- Ilaprazole Impurity 122 (CAS CATO-C4X-1130122)
- [(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-methoxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate (CAS 73646-17-0)
- tert-Butyl (3-(trifluoromethyl)-1H-pyrazol-4-yl)carbamate (CAS 2247207-77-6)
- N-Boc-4-methylene-L-proline (CAS 84348-38-9)
- 3-(1H-Indol-4-yl)-N,N-dimethylpropanethioamide (CAS 938185-59-2)
- 7-(1,3-Dimethyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 1002243-77-7)
- 2-(5-Bromothiophen-2-yl)-2-(4-(tert-butoxycarbonyl)-1,4-diazepan-1-yl)acetic acid (CAS 834884-89-8)
- 2-[3-(Trifluoromethyl)phenyl]pyrrole (CAS 41819-49-2)
- 1-(4-Nitrophenyl)indeno[1,2-c]pyrazol-4(1H)-one (CAS 141717-44-4)
- N-[4-({[amino(imino)methyl]amino}sulfonyl)phenyl]acetamide (CAS 19077-97-5)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com