Ilaprazole Impurity 122 CAS CATO-C4X-1130122
| CAS No. | CATO-C4X-1130122 |
| Molecular Formula | C18H15ClN4S |
| Molecular Weight | 354.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ilaprazole Impurity 122 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ilaprazole Impurity 122 (CAS CATO-C4X-1130122, C18H15ClN4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ilaprazole Impurity 122 (C18H15ClN4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15ClN4S |
| Molecular Weight | 354.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ilaprazole Standards
- Ilaprazole Impurity 103 (CAS CATO-C4X-1130103)
- Ilaprazole Impurity 212 (CAS CATO-C4X-1130212)
- Ilaprazole Impurity 23 (CAS CATO-C4X-113023)
- Ilaprazole Impurity 172 (CAS CATO-C4X-1130172)
- Ilaprazole Impurity 140 (CAS CATO-C4X-1130140)
- Ilaprazole Impurity 12 (CAS CATO-C4X-113012)
- Ilaprazole Impurity 160 (CAS CATO-C4X-1130160)
- Ilaprazole Impurity 17 (CAS 172152-35-1)
Recommended Standards
- 6-((6-Chloropyridin-3-yl)methyl)-5,7-dimethyl-3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidine (CAS 866040-38-2)
- Tert-butyl (1-(2-(4-chlorophenyl)-2-hydroxyethyl)piperidin-4-yl)carbamate (CAS 1338691-10-3)
- 4-((2-Chloro-3-phenylallylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-88-8)
- 2-Chloro-6-(4-morpholinylcarbonyl)-N-(1,1,3,3-tetramethylbutyl)-4-pyrimidinamine (CAS 1365838-65-8)
- Ambroxol Impurity 97 (CAS CATO-C4X-108597)
- Polidocanol Impurity 6 (CAS CATO-C4X-29446)
- Cyproheptadine Impurity 2 (CAS 2222-33-5)
- 4-[(4-Chlorophenyl)sulfanyl]-5H-pyrimido[5,4-b]indole (CAS 320420-19-7)
- N'-(Furan-2-ylmethylene)-2-(naphthalen-2-yloxy)acetohydrazide (CAS 303085-70-3)
- Rosuvastatin impurity 246 (CAS 894788-00-2)
- tert-Butyl 3-((1-(pyridin-2-yl)ethyl)amino)piperidine-1-carboxylate (CAS 1289385-48-3)
- Ethyl 4-Hydroxybenzofuran-6-carboxylate (CAS 494868-82-5)
- 3-Phenylbenzo[d]thiazole-2(3H)-thione (CAS 24097-02-7)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
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