4-(([1,1'-Biphenyl]-4-ylmethylene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione CAS 478256-37-0
| CAS No. | 478256-37-0 |
| Molecular Formula | C22H18N4S |
| Molecular Weight | 370.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(([1,1'-Biphenyl]-4-ylmethylene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-37-0), a certified reference material (molecular formula C22H18N4S, MW 370.47 g/mol) for analytical method development and quality control.
Based on its molecular formula C22H18N4S, 4-(([1,1'-Biphenyl]-4-ylmethylene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 370.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18N4S |
| Molecular Weight | 370.47 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Biphenyl Standards
- 1-([1,1'-Biphenyl]-4-yl)-3-(4-phenylpiperazin-1-yl)propan-1-one (CAS 157637-84-8)
- 3,3'-([1,1'-Biphenyl]-4,4'-diylbis(oxy))dianiline (CAS 105112-76-3)
- 4-([1,1'-Biphenyl]-4-yl)-2-amino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 337496-58-9)
- 1,2-Di([1,1'-biphenyl]-4-yl)disulfane (CAS 19813-92-4)
- 1-([1,1'-Biphenyl]-4-yl)-3-((3,4-dichlorophenyl)amino)propan-1-one (CAS 882748-75-6)
- 2-([1,1'-Biphenyl]-4-yloxy)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 302551-12-8)
- 5-(([1,1'-Biphenyl]-4-yloxy)methyl)-N-(2,4-dimethylphenyl)-1,3,4-oxadiazol-2-amine (CAS 126006-85-7)
- 4-([1,1'-Biphenyl]-4-yl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1707571-31-0)
Recommended Standards
- 3-Methyl-4-(2-(4-methylpiperazin-1-yl)acetyl)-4,9-dihydro-10H-benzo[b]thieno[3,4-e][1,4]diazepin-10-one (CAS 80880-90-6)
- 5-[(4-Methylphenyl)sulfanyl]-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (CAS 956744-37-9)
- 2,5-Dimethyl-1-(2-{7-phenylpyrazolo[1,5-a]pyrimidin-2-yl}thiophen-3-yl)-1H-pyrrole (CAS 478258-98-9)
- 5-Ethyl-4-(1-(phenylsulfonyl)ethyl)-1-(p-tolyl)-1,3-dihydro-2H-imidazol-2-one (CAS 477848-65-0)
- Methyl 2-cyclopentylthiazole-5-carboxylate (CAS 1369840-90-3)
- 2-(4-Chlorophenyl)sulfonylpyridine-3-carbaldehyde (CAS 1161864-76-1)
- N-[3-Cyano-4-(4-methylphenyl)-4H-benzo[h]chromen-2-yl]-N,N-dimethyliminoformamide (CAS 860787-52-6)
- Tolcapone 5-amino-3-O-sulfate (CAS 254902-29-9)
- 5,6-Dimethyl-2-propyl-2,3-dihydropyrazine (CAS 72671-98-8)
- PD 128907 (CAS 123594-64-9)
- 3-[(3-Chlorophenyl)sulfanyl]-6-[(2,4-dichlorophenyl)methyl]pyridazine (CAS 241488-52-8)
- 1142214-90-1 2,2-Dimethyl-3-({4-[(E)-2-phenylvinyl]piperazin-1-yl}carbonyl)cyclopropanecarboxylic acid 9453AC C19H24N2O3 (CAS 1142214-90-1)
- Anagliptin (CAS 739366-20-2)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com