4-((2-Chloro-5-nitrobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione CAS 478256-40-5
| CAS No. | 478256-40-5 |
| Molecular Formula | C16H12ClN5O2S |
| Molecular Weight | 373.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 4-((2-Chloro-5-nitrobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 373.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-((2-Chloro-5-nitrobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-40-5), a certified reference material (molecular formula C16H12ClN5O2S, MW 373.82 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-((2-Chloro-5-nitrobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12ClN5O2S |
| Molecular Weight | 373.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(2,6-dimethylphenyl)thiourea (CAS 326815-16-1)
- 4-((4-Chloro-3-nitrobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-23-4)
- 4-(3-Chloro-5-((4-cyanophenyl)amino)phenoxy)-3,5-dimethylbenzonitrile (CAS 1242268-27-4)
- 2-((5-Chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)thio)-1-(4-fluorophenyl)ethan-1-one (CAS 685504-95-4)
- 2-Chloro-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]-2-phenylacetamide (CAS 565191-94-8)
- 3-Chloro-4-(diphenylamino)-6-phenyl-2H-pyran-2-one (CAS 70486-07-6)
- Ethyl 4-chloro-6-((dimethylamino)methyl)-5-hydroxy-2-phenylbenzofuran-3-carboxylate (CAS 55878-90-5)
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Recommended Standards
- 3-Amino-2,4,6-tribromobenzoic acid (CAS 6628-84-8)
- 2-((4-Chlorobenzyl)amino)-1,1-bis(4-fluorophenyl)ethanol (CAS 338770-95-9)
- 4-[(1Z/E)-1-(4-chlorophenyl)-3-morpholin-4-yl-3-oxoprop-1-enyl]-2-methoxyphenol (CAS 1786462-97-2)
- Dacomitinib Impurity 27 (CAS CATO-C4X-208627)
- Ethyl 2-((2-methoxy-5-methylphenyl)amino)-2-oxoacetate (CAS 24439-42-7)
- Escin IA (CAS 123748-68-5)
- 3-(4-Nitrophenyl)-1H-pyridin-2-one (CAS 660440-56-2)
- 2-[4-(2-methoxy-5-methylphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetic acid (CAS 1152642-00-6)
- (OC-6-22)-(Dipyrido[3,2-a:2',3'-c]phenazine-κN4,κN5)bis(1,10-phenanthroline-κN1,κN10)ruthenium (CAS 92543-42-5)
- N-benzyl-2-hydroxy-N-methylbenzamide (CAS 64302-57-4)
- 4-Thujanol (CAS 546-79-2)
- Z-Trp(Boc)-OH (CAS 131829-26-0)
- n-(2-Aminocyclopropyl)ethanesulfonamide (CAS 1157099-55-2)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
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