6-Chloro-N-methyl-2-(methylsulfanyl)-N-phenylpyrimidin-4-amine CAS 478258-44-5
| CAS No. | 478258-44-5 |
| Molecular Formula | C12H12ClN3S |
| Molecular Weight | 265.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-N-methyl-2-(methylsulfanyl)-N-phenylpyrimidin-4-amine.
CATO supplies 6-Chloro-N-methyl-2-(methylsulfanyl)-N-phenylpyrimidin-4-amine (CAS 478258-44-5), a certified reference material (molecular formula C12H12ClN3S, MW 265.76 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 6-Chloro-N-methyl-2-(methylsulfanyl)-N-phenylpyrimidin-4-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 265.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-N-methyl-2-(methylsulfanyl)-N-phenylpyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12ClN3S |
| Molecular Weight | 265.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-((2-methoxybenzyl)thio)pyridine (CAS 1346707-46-7)
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- 4-Chloro-2-((4-methoxybenzyl)thio)pyridine (CAS 1346707-48-9)
- methyl 4-chloro-2-(methylsulfanyl)pyrrolo[2,1-f][1,2,4]triazine-7-carboxylate (CAS 1823484-81-6)
- 2-chloro-N-[phenyl(thien-2-yl)methyl]acetamide (CAS 923709-46-0)
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Recommended Standards
- 5-(4-Chlorophenyl)-4-(2-methylprop-2-en-1-yl)-4h-1,2,4-triazole-3-thiol (CAS 305337-31-9)
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- 4-Allyl-5-(4-chlorobenzyl)-4H-1,2,4-triazole-3-thiol (CAS 667437-95-8)
- ethyl 2-amino-4-chlorothieno[2,3-d]pyrimidine-6-carboxylate (CAS 847560-46-7)
- 4-Amino-3-methyl-1H-pyrazole-5-carboxylic acid (CAS 94993-81-4)
- 4,6-Dichloro-2-(1H-pyrazol-1-yl)pyrimidine (CAS 1017781-89-3)
- Gnetol (CAS 86361-55-9)
- 6653-91-4 Imidazo[1,2-b]pyridazin-6-ylhydrazine hydrochloride (CAS 6653-91-4)
- 1-[(4-acetylphenyl)sulfonyl]piperidine-2-carboxylic acid (CAS 809240-69-5)
- 1-(Quinazolin-4-yl)piperidin-4-amine (CAS 853680-04-3)
- Sodium (2R,3S,4R,5R)-2,4,5,6-tetrahydroxy-1-oxohexan-3-yl sulfate (CAS 89830-83-1)
- Benzyl 2-(piperidin-4-yl)acetate (CAS 180182-05-2)
- 1-((1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl)piperidine-3-carboxylic acid (CAS 899703-32-3)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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