(5Z)-3-Ethyl-5-[(4-methoxyphenyl)methylidene]-2-[(4H-1,2,4-triazol-4-yl)imino]-1,3-thiazolidin-4-one CAS 478258-91-2
| CAS No. | 478258-91-2 |
| Molecular Formula | C15H15N5O2S |
| Molecular Weight | 329.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(5Z)-3-Ethyl-5-[(4-methoxyphenyl)methylidene]-2-[(4H-1,2,4-triazol-4-yl)imino]-1,3-thiazolidin-4-one (CAS 478258-91-2) is a high-purity analytical reference standard with the molecular formula C15H15N5O2S and a molecular weight of 329.38 g/mol.
The molecular framework of (5Z)-3-Ethyl-5-[(4-methoxyphenyl)methylidene]-2-[(4H-1,2,4-triazol-4-yl)imino]-1,3-thiazolidin-4-one (C15H15N5O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15N5O2S |
| Molecular Weight | 329.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Recommended Standards
- 2-Methyl-2-((4-oxo-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)thio)propanamide (CAS 1892594-93-2)
- 1-(2-Ethoxyphenyl)-5-methyl-N-(thiazol-2-yl)-1H-1,2,3-triazole-4-carboxamide (CAS 878734-74-8)
- 6-Methyl-N-(4-(methylthio)benzyl)-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]pyrazine-3-carboxamide (CAS 1396864-16-6)
- 2-((4-Amino-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(m-tolyl)acetamide (CAS 811468-71-0)
- methyl trans-3-formylcyclobutanecarboxylate (CAS 1410810-14-8)
- Kifunensine (CAS 109944-15-2)
- 2-[3-Cyano-4-(3-hydroxy-2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid (CAS 887945-96-2)
- (Chloromethyl)triphenylphosphonium iodide (CAS 68089-86-1)
- 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(m-tolyl)acetamide (CAS 477330-41-9)
- 1-(2-Isopropoxyphenyl)ethan-1-one (CAS 70201-54-6)
- 1-(Spiro[2.2]pentan-1-yl)ethan-1-one (CAS 249563-62-0)
- tert-Butyl ((S)-1-(((S)-1-cyclohexyl-2-((S)-2-(4-(4-hydroxybenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate (CAS 2222354-11-0)
- Perchlorotriphenylmethyl radical (CAS 4070-01-3)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
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