2-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine CAS 478258-90-1
| CAS No. | 478258-90-1 |
| Molecular Formula | C22H17FN4S |
| Molecular Weight | 388.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine.
2-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine (CAS 478258-90-1), molecular formula C22H17FN4S and molecular weight 388.46 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C22H17FN4S, 2-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 388.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-3-yl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17FN4S |
| Molecular Weight | 388.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dimethyl Standards
- 2-(3-(2,5-Dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-09-8)
- N-(4-{[(2,6-Dimethyl-4-pyrimidinyl)amino]sulfonyl}phenyl)-2-thiophenecarboxamide (CAS 302937-92-4)
- 2-(2,5-Dimethyl-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-3-yl)-2-oxoethyl 2-(methylthio)nicotinate (CAS 561049-91-0)
- 4,6-Dimethyl-N-[(E)-(4-methylphenyl)methylidene]-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carbohydrazide (CAS 478029-11-7)
- N-(7,10-dimethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepin-2-yl)-4-methoxybenzamide (CAS 866152-13-8)
- 1-(2,5-Dimethyl-1-(thiophen-2-ylmethyl)-1H-pyrrol-3-yl)-2-(5-fluoro-2-nitrophenoxy)ethan-1-one (CAS 852905-13-6)
- n-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)-4-nitrobenzenesulfonamide (CAS 301332-17-2)
- 4-(5,5-Dimethyl-1,3-dioxan-2-yl)-1-(2-iodophenyl)butan-1-one (CAS 898785-54-1)
Recommended Standards
- 1-Amino-4-(benzo[d]thiazol-2-ylthio)anthracene-9,10-dione (CAS 3767-68-8)
- 2-(2-(2-Oxobenzo[d]thiazol-3(2H)-yl)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid (CAS 755018-06-5)
- 1,5-Bis(4-methoxyphenyl)-3-phenylpentane-1,5-dione (CAS 82672-13-7)
- 2-(2,4-Diphenylthiazol-5-yl)-N-(4-fluorophenyl)acetamide (CAS 339277-54-2)
- N-Isopropyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxamide (CAS 952734-32-6)
- 3-((4-Chlorophenyl)sulfonyl)-4,6-dimethylpyridin-2(1H)-one (CAS 321431-06-5)
- trans-4-Cyanophenyl 4-pentylcyclohexanecarboxylate (CAS 62439-35-4)
- 8-(4-Chlorophenyl)-6-methyl-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile (CAS 860784-22-1)
- (PB-7-11-2344'3')-Dichloro[(4aS,13aS,17aS,21aS)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-11,7-nitrilo-7H-dibenzo[b,h][1,4,7,10]tetraazacycloheptadecine-κN5,κN13,κN18,κN21,κN22]manganese (CAS 435327-40-5)
- M-ACetylphenyl-peg5-t-butyl ester (CAS 2110448-95-6)
- 4-Chloro-5-morpholinopyridazin-3-ol (CAS 944-88-7)
- 3-(3-methylphenoxy)aniline (CAS 116289-59-9)
- Methyl 2-((methylamino)methyl)-1H-benzo[d]imidazole-7-carboxylate (CAS 1258071-11-2)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com