| CAS No. | 478261-48-2 |
| Molecular Formula | C19H10ClF3N2O |
| Molecular Weight | 374.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
6-(4-Chlorophenyl)-2-hydroxy-4-[2-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (C19H10ClF3N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
6-(4-Chlorophenyl)-2-hydroxy-4-[2-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478261-48-2), molecular formula C19H10ClF3N2O and molecular weight 374.74 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(4-Chlorophenyl)-2-hydroxy-4-[2-(trifluoromethyl)phenyl]pyridine-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C19H10ClF3N2O |
| Molecular Weight | 374.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |