5-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile CAS 338955-27-4
| CAS No. | 338955-27-4 |
| Molecular Formula | C19H10ClF3N2O |
| Molecular Weight | 374.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C19H10ClF3N2O, 5-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 374.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile (CAS 338955-27-4), molecular formula C19H10ClF3N2O and molecular weight 374.74 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H10ClF3N2O |
| Molecular Weight | 374.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 4-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile (CAS 339103-66-1)
- 4-(4-Chlorophenyl)-2-hydroxy-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478261-46-0)
- 4-(4-Chlorophenyl)-2-hydroxy-6-[4-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478261-47-1)
- 6-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile (CAS 252059-11-3)
- 6-(4-Chlorophenyl)-2-hydroxy-4-[2-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478261-48-2)
- 2-(5-(4-Chlorophenyl)-1H-pyrazol-1-yl)-3-(trifluoromethyl)quinoxaline (CAS 321538-11-8)
- 4-[(4-Chlorophenyl)methyl]-2-(2,6-difluorophenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile (CAS 672951-30-3)
- N-(4-chlorophenyl)-1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 242797-43-9)
Recommended Standards
- 7-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-phenylpyrazolo[1,5-a]pyrimidine (CAS 1092345-56-6)
- 2-chloro-N-(2,3-dimethoxybenzyl)-4-(trifluoromethyl)nicotinamide (CAS 680213-87-0)
- 3-Chloro-2-{3-phenylpyrazolo[1,5-a]pyrimidin-7-yl}-5-(trifluoromethyl)pyridine (CAS 1092345-99-7)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(3,4-dimethoxyphenyl)acetamide (CAS 338407-50-4)
- 6-fluoro-4,5-dimethylpyridazin-3-amine (CAS 2060019-79-4)
- 2,2-Diphenylethylisothiocyanate (CAS 34634-22-5)
- 3-(Piperidin-3-yl)-1h-1,2,4-triazol-5-amine (CAS 1248128-33-7)
- 2-(Pyridin-2-yl)pyrimidin-4-amine (CAS 61310-37-0)
- 2-Amino-4,7,7-trimethyl-7,8-dihydroquinazolin-5(6H)-one (CAS 126993-17-7)
- Sodium (Z)-1-cyanoprop-1-en-2-olate (CAS 1199252-10-2)
- Osimertinib Impurity N3 (CAS 1820891-36-8)
- 4-(2,3-Dihydrobenzo[b][1,4]dioxine-6-carbonyl)-3-hydroxy-1-(2-morpholinoethyl)-5-(pyridin-3-yl)-1H-pyrrol-2(5H)-one (CAS 618071-69-5)
- 2-Bromobenzofuran-6-ol (CAS 112768-49-7)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
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