3-(3-Chlorophenyl)-4-(methylthio)-2-thioxo-2,3-dihydrothiazole-5-carbonitrile CAS 478261-55-1
| CAS No. | 478261-55-1 |
| Molecular Formula | C11H7ClN2S3 |
| Molecular Weight | 298.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 3-(3-Chlorophenyl)-4-(methylthio)-2-thioxo-2,3-dihydrothiazole-5-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 298.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
3-(3-Chlorophenyl)-4-(methylthio)-2-thioxo-2,3-dihydrothiazole-5-carbonitrile (CAS 478261-55-1), molecular formula C11H7ClN2S3 and molecular weight 298.83 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClN2S3 |
| Molecular Weight | 298.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-4-(methylsulfanyl)-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carbonitrile (CAS 866143-60-4)
- 3-(1-(4-Chlorophenyl)cyclobutyl)-5,6,7,8-tetrahydrocinnoline (CAS 918873-18-4)
- 3-(4-Chlorophenyl)-5-(methylsulfanyl)thiophene-2-carbohydrazide (CAS 860649-93-0)
- 4-((4-Chlorophenyl)thio)-5-methoxy-2-(methylthio)pyrimidine (CAS 338954-61-3)
- Methyl 3-(4-chlorophenyl)-5-(methylsulfanyl)thiophene-2-carboxylate (CAS 477857-89-9)
- 5-((3-Chlorophenyl)amino)-3-isobutylthiazolidine-2,4-dione (CAS 1046756-50-6)
- 3-((4-Chlorophenyl)thio)-2-methyl-1H-indole-5-carbonitrile (CAS 628736-65-2)
- 4-(4-Chlorophenyl)-2-(phenylsulfanyl)pyrimidine (CAS 339106-03-5)
Recommended Standards
- 2-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-1,3-benzothiazole (CAS 339018-61-0)
- Tulobuterol Impurity 7 (CAS CATO-C4X-21347)
- 4-Chloro-6-((4-methoxyphenyl)thio)-2-(methylthio)pyrimidine (CAS 478258-40-1)
- Xylometazoline EP Impurity A (CAS 81201-80-1)
- 6-Chloro-N-(2,2-dimethoxyethyl)imidazo[1,2-a]pyridine-2-carboxamide (CAS 882748-09-6)
- Methyl[(5-phenyl-1,2-oxazol-3-yl)methyl]amine hydrochloride (CAS 852227-91-9)
- 5-Methyl-4-isoxazolesulfonyl chloride (CAS 321309-26-6)
- ethyl 2-[3-(methoxymethyl)-1,2,4-oxadiazol-5-yl]acetate (CAS 1423031-04-2)
- 2-Methoxy-4,6-dimethylpyridine (CAS 45798-56-9)
- Methyl 3-Amino-4,4-dimethylpentanoate (CAS 1273387-45-3)
- 6-(Cyclohexylamino)-1,3-dimethyl-5-(4-nitrophenyl)furo[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 503160-55-2)
- 7-(3-Chlorothiophen-2-yl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxylic acid (CAS 477864-90-7)
- 3,3',3'',3'''-(((1,2-Phenylenebis(oxy))bis(ethane-2,1-diyl))bis(azanetriyl))tetrakis(1-((9H-carbazol-4-yl)oxy)propan-2-ol) (CAS 1391052-20-2)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
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