4-(Methylthio)-2-thioxo-3-(p-tolyl)-2,3-dihydrothiazole-5-carbonitrile CAS 478261-56-2
| CAS No. | 478261-56-2 |
| Molecular Formula | C12H10N2S3 |
| Molecular Weight | 278.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Methylthio)-2-thioxo-3-(p-tolyl)-2,3-dihydrothiazole-5-carbonitrile (CAS 478261-56-2), molecular formula C12H10N2S3 and molecular weight 278.42 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Methylthio)-2-thioxo-3-(p-tolyl)-2,3-dihydrothiazole-5-carbonitrile (C12H10N2S3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10N2S3 |
| Molecular Weight | 278.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
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Recommended Standards
- 3-Methyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one (CAS 2081858-87-7)
- N-(sec-butyl)-4-(pyridin-2-yl)piperazine-1-carbothioamide (CAS 905479-27-8)
- (7-((tert-Butyldimethylsilyl)oxy)benzofuran-5-yl)methanol (CAS 831222-97-0)
- Phenyl(4-((trimethylsilyl)ethynyl)phenyl)methanone (CAS 220659-84-7)
- 3,5-Dimethyl-1-(4-methylbenzyl)-1h-pyrazol-4-amine (CAS 514816-02-5)
- 5-((Dimethylamino)methyl)-3-methylbenzofuran-2-carboxylic acid hydrochloride (CAS 1266694-39-6)
- 4-methylpentanimidamide hydrochloride (CAS 857809-07-5)
- 2-(2-Aminoethyl)-6-chloropyridin-4-amine (CAS 1393550-12-3)
- (5S)-2,7-diazaspiro[4.4]nonan-1-one;hydrochloride (CAS 2518063-72-2)
- 3-(Aminomethyl)-6-bromo-4-(difluoromethyl)pyridin-2-amine (CAS 1805334-32-0)
- (2,6-Diethylphenyl)methanamine hydrochloride (CAS 107694-43-9)
- 2-nitro-4-(thiophen-2-yl)aniline (CAS 405170-93-6)
- N-(4-Formyl-3-hydroxyphenyl)benzenesulfonamide (CAS 62119-69-1)
- Peptide 433 (CAS CATO-CPTD788433)
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