Ethyl 6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-4-(4-chlorophenyl)-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate CAS 478261-86-8
| CAS No. | 478261-86-8 |
| Molecular Formula | C22H17Cl2F3N2O3S |
| Molecular Weight | 517.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-4-(4-chlorophenyl)-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate.
CATO supplies Ethyl 6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-4-(4-chlorophenyl)-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate (CAS 478261-86-8), a certified reference material (molecular formula C22H17Cl2F3N2O3S, MW 517.35 g/mol) for analytical method development and quality control.
Ethyl 6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-4-(4-chlorophenyl)-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate (C22H17Cl2F3N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-4-(4-chlorophenyl)-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H17Cl2F3N2O3S |
| Molecular Weight | 517.35 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 4-Chloro-N-(2-(8-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)-2-oxoethyl)benzamide (CAS 400079-21-2)
- Methyl 2-(2-(4-chloro-2-methylphenoxy)acetamido)-5-((4-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505096-47-9)
- (2Z)-3-[4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]-1-(pyridin-4-yl)prop-2-en-1-one (CAS 338406-46-5)
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- (E)-4-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-(2-(4-methoxybenzylidene)hydrazinyl)pyrido[2,3-b]pyrazin-3(4H)-one (CAS 338412-03-6)
- 6-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)-4-methyl-2-(3-(trifluoromethyl)phenyl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 477709-55-0)
- 2-Chloro-4-methanesulfonyl-N-{4-[3-(trifluoromethyl)benzenesulfonyl]phenyl}benzamide (CAS 339105-03-2)
Recommended Standards
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