3-Cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide CAS 478262-15-6

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

3-Cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide (CAS 478262-15-6) is a high-purity analytical reference standard with the molecular formula C10H9N5O and a molecular weight of 215.21 g/mol.

The molecular framework of 3-Cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide (C10H9N5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), 3-Cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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