1-(3-Bromophenoxy)-2-fluoro-4-nitrobenzene CAS 74660-86-9
| CAS No. | 74660-86-9 |
| Molecular Formula | C12H7BrFNO3 |
| Molecular Weight | 312.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Bromophenoxy)-2-fluoro-4-nitrobenzene (CAS 74660-86-9) is a high-purity analytical reference standard with the molecular formula C12H7BrFNO3 and a molecular weight of 312.09 g/mol.
1-(3-Bromophenoxy)-2-fluoro-4-nitrobenzene (C12H7BrFNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-Bromophenoxy)-2-fluoro-4-nitrobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7BrFNO3 |
| Molecular Weight | 312.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromophenoxy Standards
- 1-(2-Bromophenoxy)-4-fluoro-2-nitrobenzene (CAS 1019508-64-5)
- 1-(4-Bromophenoxy)-4-fluoro-2-nitrobenzene (CAS 15211-98-0)
- 1-(4-Bromophenoxy)-2-fluoro-4-nitrobenzene (CAS 189181-33-7)
- 2-(3-Bromophenoxy)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1252311-93-5)
- 2-(4-Bromophenoxy)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1306051-38-6)
- N-[2-(4-Bromophenoxy)ethyl]-2,2,2-trifluoroacetamide (CAS 377745-03-4)
- 1-(3-(3-Bromophenoxy)propyl)-4-methylpiperidine (CAS 1704065-41-7)
- 1-(3-(4-Bromophenoxy)propyl)-4-methylpiperidine (CAS 401805-14-9)
Recommended Standards
- 2-(2-Bromo-4-fluorophenoxy)pyridine-3-carboxylic acid (CAS 954563-46-3)
- 4-Bromo-5-cyano-6-(difluoromethyl)pyridine-3-sulfonamide (CAS 1806992-40-4)
- 2-Bromo-1-(4-fluorophenoxy)-4-nitrobenzene (CAS 477856-83-0)
- 6-Bromo-5-cyano-4-(difluoromethyl)pyridine-3-sulfonamide (CAS 1806991-85-4)
- Δ12-Prostaglandin-d (CAS 64072-89-5)
- Ethyl1,5,6,7-tetrahydropyrano[3,2-b]pyrrole-2-carboxylate (CAS 2231041-25-9)
- Benzyl 8-(methylamino)-2-azaspiro[4.5]Decane-2-carboxylate (CAS 2306272-88-6)
- 2-(Tetrahydro-2H-pyran-2-yl)ethanol (CAS 38786-79-7)
- 2-Methoxy-4-nitroacridin-9(10H)-one (CAS 89974-79-8)
- 4-((6-Chloropyridin-3-yl)diazenyl)-1-hydroxy-3H-isochromen-3-one (CAS 939762-09-1)
- 4-Cyclopropoxy-2-ethyl-1-nitrobenzene (CAS 1243482-16-7)
- Bis(1,3-divinyl-1,1,3,3-tetramethyldisiloxane)platinum (CAS 81032-58-8)
- 3-Phenyl-1H-pyrazolo[4,3-c]pyridine (CAS 113277-54-6)
- Dulaglutide (CAS 923950-08-7)
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