N-[(1E)-{[(2-bromophenyl)methoxy]imino}methyl]-4-methoxy-2-phenoxypyridine-3-carboxamide CAS 478262-48-5
| CAS No. | 478262-48-5 |
| Molecular Formula | C21H18BrN3O4 |
| Molecular Weight | 456.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-[(1E)-{[(2-bromophenyl)methoxy]imino}methyl]-4-methoxy-2-phenoxypyridine-3-carboxamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-[(1E)-{[(2-bromophenyl)methoxy]imino}methyl]-4-methoxy-2-phenoxypyridine-3-carboxamide (CAS 478262-48-5) is a high-purity analytical reference standard with the molecular formula C21H18BrN3O4 and a molecular weight of 456.29 g/mol.
The molecular framework of N-[(1E)-{[(2-bromophenyl)methoxy]imino}methyl]-4-methoxy-2-phenoxypyridine-3-carboxamide (C21H18BrN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H18BrN3O4 |
| Molecular Weight | 456.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
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