5-(3-Chlorothiophen-2-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazole CAS 478488-64-1
| CAS No. | 478488-64-1 |
| Molecular Formula | C11H6ClN3OS |
| Molecular Weight | 263.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(3-Chlorothiophen-2-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazole (CAS 478488-64-1), molecular formula C11H6ClN3OS and molecular weight 263.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(3-Chlorothiophen-2-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazole (C11H6ClN3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6ClN3OS |
| Molecular Weight | 263.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorothiophen Standards
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Recommended Standards
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- 5-Chloro-8-(1,2,3-thiadiazol-5-yloxy)quinoline (CAS 439120-55-5)
- 7-(trifluoromethyl)quinolin-4-amine (CAS 243666-11-7)
- 4-Methyl-4-nitropentan-1-ol (CAS 5215-92-9)
- 6-methylmorpholine-2-carboxamide (CAS 1824547-84-3)
- MEthyl 3-[(3-nitrophenyl)formamido]propanoate (CAS 60247-40-7)
- 2-(Naphthalen-1-yl)propanenitrile (CAS 24168-42-1)
- 1-Benzyl-N-(3,4-difluorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-76-3)
- Dyclonine Impurity 6 (CAS 3180-09-4)
- Methyl 2-(cyclopropylamino)-3-(4-iodo-1h-pyrazol-1-yl)propanoate (CAS 1339425-90-9)
- [3-methoxy-4-(2-methoxyethoxy)phenyl]methanamine hydrochloride (CAS 1171624-38-6)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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