1H-Imidazol-4-amine sulfate CAS 480438-23-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1H-Imidazol-4-amine sulfate.

1H-Imidazol-4-amine sulfate (CAS 480438-23-1), molecular formula H2O4SC3H5N3 and molecular weight 181.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1H-Imidazol-4-amine sulfate (H2O4SC3H5N3) is characterized by an amide group, a sulfone group, a carboxylic acid group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1H-Imidazol-4-amine sulfate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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