1-(4-(Trifluoromethyl)benzyl)indoline-2,3-dione CAS 522612-12-0

Purity 97%+In StockPharmaceutical Standards
CAS No.522612-12-0
Molecular FormulaC16H10F3NO2
Molecular Weight305.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-(Trifluoromethyl)benzyl)indoline-2,3-dione CAS 522612-12-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-(Trifluoromethyl)benzyl)indoline-2,3-dione.

CATO supplies 1-(4-(Trifluoromethyl)benzyl)indoline-2,3-dione (CAS 522612-12-0), a certified reference material (molecular formula C16H10F3NO2, MW 305.25 g/mol) for analytical method development and quality control.

The molecular framework of 1-(4-(Trifluoromethyl)benzyl)indoline-2,3-dione (C16H10F3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(4-(Trifluoromethyl)benzyl)indoline-2,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H10F3NO2
Molecular Weight305.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF-containing
Nitrogen Atoms1

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