2-Ethoxy-4-fluorophenylboronic acid CAS 480438-58-2

Purity 97%+In StockPharmaceutical Standards
CAS No.480438-58-2
Molecular FormulaC8H10BFO3
Molecular Weight183.97 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Ethoxy-4-fluorophenylboronic acid CAS 480438-58-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 183.97 g/mol gives 2-Ethoxy-4-fluorophenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) is a high-purity analytical reference standard with the molecular formula C8H10BFO3 and a molecular weight of 183.97 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Ethoxy-4-fluorophenylboronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Ethoxy-4-fluorophenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H10BFO3
Molecular Weight183.97 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2025
Halogen ContentF-containing

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