Edoxaban Impurity 12 CAS 480450-71-3
| CAS No. | 480450-71-3 |
| Molecular Formula | C17H27N5O2S |
| Molecular Weight | 365.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Edoxaban Impurity 12.
CATO supplies Edoxaban Impurity 12 (CAS 480450-71-3), a pharmacopoeial impurity reference standard (molecular formula C17H27N5O2S, MW 365.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Edoxaban Impurity 12 (C17H27N5O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Edoxaban Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H27N5O2S |
| Molecular Weight | 365.49 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
- Edoxaban Impurity 75 (CAS 1255529-31-7)
- Edoxaban Impurity N5 (CAS 365997-36-0)
- Edoxaban Impurity 28 (CAS 929693-31-2)
- Edoxaban Impurity 54 (CAS 482375-18-8)
- Edoxaban Impurity 3 (CAS 480452-37-7)
- Edoxaban Impurity 70 (CAS CATO-C4X-106370)
- Edoxaban Impurity 72 (CAS 365998-34-1)
- Edoxaban Impurity 32 (CAS 1461714-66-8)
Recommended Standards
- Pericyazine (CAS 2622-26-6)
- Tridecyl (2-(trimethylammonio)ethyl) phosphate (CAS 85775-42-4)
- N-Mesityl-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide (CAS 851131-36-7)
- ((2S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-2-yl)methanol (CAS 862179-58-6)
- Biapenem impurity 17 (CAS CATO-C4X-227317)
- Progesterone Impurity 85 (CAS 151122-70-2)
- Orforglipron Impurity 16 (CAS CATO-C4X-323416)
- 3-(5-{[(6z)-2-(2-chlorophenyl)-5-imino-7-oxo-5h,6h,7h-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-ylidene]methyl}furan-2-yl)benzoic acid (CAS 356075-07-5)
- 3-Amino-4-chloro-n-(4-iodophenyl)benzene-1-sulfonamide (CAS 380569-55-1)
- 6,7-Dihydro-3-hydroxy-5H-cyclopenta[b]pyridin-5-one (CAS 1211523-07-7)
- Methyl 2-(2-bromo-4-methylphenyl)acetate (CAS 77053-52-2)
- N-benzyl-2-(methylthio)pyrimidin-4-amine (CAS 91719-61-8)
- (S)-Dimethyl 2-(((benzyloxy)carbonyl)amino)succinate (CAS 35909-93-4)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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