3-(4-Hydroxy-3-methoxyphenyl)-2-(2H-tetrazol-5-yl)-N-(3-(trifluoromethyl)phenyl)propanamide CAS 483995-89-7
| CAS No. | 483995-89-7 |
| Molecular Formula | C18H16F3N5O3 |
| Molecular Weight | 407.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Hydroxy-3-methoxyphenyl)-2-(2H-tetrazol-5-yl)-N-(3-(trifluoromethyl)phenyl)propanamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Hydroxy-3-methoxyphenyl)-2-(2H-tetrazol-5-yl)-N-(3-(trifluoromethyl)phenyl)propanamide (CAS 483995-89-7) is a high-purity analytical reference standard with the molecular formula C18H16F3N5O3 and a molecular weight of 407.35 g/mol.
Based on its molecular formula C18H16F3N5O3, 3-(4-Hydroxy-3-methoxyphenyl)-2-(2H-tetrazol-5-yl)-N-(3-(trifluoromethyl)phenyl)propanamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 407.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Hydroxy-3-methoxyphenyl)-2-(2H-tetrazol-5-yl)-N-(3-(trifluoromethyl)phenyl)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16F3N5O3 |
| Molecular Weight | 407.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Hydroxy Standards
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- 3-Hydroxy Fenretinide (CAS 1027233-22-2)
Recommended Standards
- Citalopram Impurity 23 (CAS 390817-87-5)
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- 3-(4-(2,4-Dichlorophenyl)thiazol-2-yl)-2-phenylthiazolidin-4-one (CAS 866048-97-7)
- 4-(1,3-Dithiolan-2-yl)phenyl 2,5-dichlorobenzene-1-sulfonate (CAS 298216-04-3)
- 2-Bromo-6-(difluoromethoxy)naphthalene (CAS 244103-47-7)
- 2,2'-(Pentane-3,3-diyl)difuran (CAS 100612-04-2)
- (R)-1-(3,5-dimethylphenyl)ethan-1-amine (CAS 737713-28-9)
- Dapagliflozin Impurity 35 (CAS 898538-17-5)
- 4-(Methoxycarbonyl)-2-(trifluoromethyl)phenylboronic Acid Pinacol Ester (CAS 1371589-09-1)
- 2-((3,4-Dichlorobenzyl)thio)-4-(3,4-dimethoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 444156-97-2)
- Ethyl (R)-4-(1-aminoethyl)benzoate (CAS 1313277-75-6)
- 2-Vinylbut-2-enal (CAS 20521-42-0)
- 5-Bromo-1-(bromomethyl)-2,3-difluorobenzene (CAS 887585-85-5)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
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