2,3,5,6-Tetrachloro-4-methoxyphenol CAS 484-67-3
| CAS No. | 484-67-3 |
| Molecular Formula | C7H4Cl4O2 |
| Molecular Weight | 261.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,3,5,6-Tetrachloro-4-methoxyphenol (CAS 484-67-3), molecular formula C7H4Cl4O2 and molecular weight 261.92 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,3,5,6-Tetrachloro-4-methoxyphenol (C7H4Cl4O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,3,5,6-Tetrachloro-4-methoxyphenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl4O2 |
| Molecular Weight | 261.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 2-Chloro-4-methoxy-6-(trichloromethyl)pyrimidine (CAS 137161-14-9)
- Tetrachloroguaiacol (CAS 2539-17-5)
- 3-chloro-1-[tris(propan-2-yl)silyl]-1H-pyrrole (CAS 130408-83-2)
- (Z)-1-Bromo-4-(2-bromovinyl)benzene (CAS 115665-68-4)
- 3-(2-Chloro-4-pyrimidinyl)benzyl Alcohol (CAS 859517-90-1)
- 4-Methylpyrrolidin-3-ol hydrochloride (CAS 1637399-49-5)
- 1-(2-Chlorobenzyl)-N-(3,4-dimethoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 320419-77-0)
- (2R,3R)-rel-2-methyl-3-Piperidinecarboxylic acid methyl ester (CAS 2455600-70-9)
- 3-(1,5-dimethyl-1H-pyrazol-4-yl)alanine (CAS 1104624-61-4)
- (2S)-1-[[2-Hydroxy-3-(trifluoromethyl)phenyl]methyl]-α,α-bis(4-methylphenyl)-2-pyrrolidinemethanol (CAS 1429648-15-6)
- N1-(2,4-dichlorobenzyl)-N1-isopropylethane-1,2-diamine (CAS 1247472-44-1)
- 2-((1S,3R)-9-Hydroxy-1-methyl-5,10-dioxo-3,4,5,10-tetrahydro-1H-benzo[g]isochromen-3-yl)acetamide (CAS 58286-55-8)
- 5-NItro-2-pyrimidinol sodium salt (CAS 1185292-89-0)
- Peptide 438 (CAS CATO-CPTD788438)
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