Vonoprazan Fumarate Impurity 74 CAS 4847-34-1
| CAS No. | 4847-34-1 |
| Molecular Formula | C6H8N2O2S |
| Molecular Weight | 172.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 172.20 g/mol gives Vonoprazan Fumarate Impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Vonoprazan Fumarate Impurity 74 (CAS 4847-34-1) is a certified pharmaceutical impurity reference standard with the molecular formula C6H8N2O2S and a molecular weight of 172.20 g/mol.
Vonoprazan Fumarate Impurity 74 (C6H8N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O2S |
| Molecular Weight | 172.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Fumarate Impurity 22 (CAS 1934459-20-7)
- Vonoprazan Impurity 188 (CAS 111480-82-1)
- Vonoprazan Impurity 189 (CAS CATO-C4X-1020189)
- Vonoprazan Impurity 54 (CAS 1421640-34-7)
- Vonoprazan Impurity 36 (CAS 56448-22-7)
- Vonoprazan Impurity 112 (CAS 881673-95-6)
- Vonoprazan Impuirty 86 (CAS 5402-21-1)
- Vonoprazan Impurity 289 (CAS CATO-C4X-1020289)
Recommended Standards
- 2-Aminobenzenesulfonamide (CAS 3306-62-5)
- Sulfadimethoxine EP Impurity E (CAS 63-74-1)
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