Vonoprazan Impurity 54 CAS 1421640-34-7
| CAS No. | 1421640-34-7 |
| Molecular Formula | C6H7NO3S |
| Molecular Weight | 173.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Vonoprazan Impurity 54 (C6H7NO3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Vonoprazan Impurity 54 (CAS 1421640-34-7, C6H7NO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7NO3S |
| Molecular Weight | 173.19 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 188 (CAS 111480-82-1)
- Vonoprazan Impurity 189 (CAS CATO-C4X-1020189)
- Vonoprazan Impurity 112 (CAS 881673-95-6)
- Vonoprazan Fumarate Impurity 22 (CAS 1934459-20-7)
- Vonoprazan Fumarate Impurity 74 (CAS 4847-34-1)
- Vonoprazan Impuirty 86 (CAS 5402-21-1)
- Vonoprazan Impurity 289 (CAS CATO-C4X-1020289)
- Vonoprazan Impurity 36 (CAS 56448-22-7)
Recommended Standards
- Celecoxib Impurity 13 (CAS 1576-43-8)
- Ceftriaxone Impurity 26 (CAS 77780-49-5)
- 3985AF 5-Methyl-3-(methylsulfonyl)-1,2,4-triazine 945915-48-0 C5H7N3O2S (CAS 945915-48-0)
- N-Nitroso Tizanidine USP Related Compound C (CAS CATO-C4X-144564)
- Meropenem Impurity 33 (CAS CATO-C4X-130933)
- Axitinib Impurity 12 (CAS CATO-C4X-107112)
- Finasteride Impurity 38 (CAS CATO-C4X-164538)
- Indium (II) chloride (CAS 13465-11-7)
- 2-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-2-methyl-1,3-dioxolane (CAS 339276-53-8)
- 2-Cyano-N-octylacetamide (CAS 39581-22-1)
- 2-Hydroxy-3-(hydroxymethyl)anthracene-9,10-dione (CAS 68243-30-1)
- 5-(Aminomethyl)-3-methoxypicolinonitrile (CAS 2377901-84-1)
- Brivudine Triphosphate (CAS 77222-61-8)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
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