6-(Adamantan-1-yl)-3-amino-N-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide CAS 488119-86-4
| CAS No. | 488119-86-4 |
| Molecular Formula | C27H28F3N3O3S |
| Molecular Weight | 531.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-(Adamantan-1-yl)-3-amino-N-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (C27H28F3N3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-(Adamantan-1-yl)-3-amino-N-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 488119-86-4) is a high-purity analytical reference standard with the molecular formula C27H28F3N3O3S and a molecular weight of 531.59 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(Adamantan-1-yl)-3-amino-N-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H28F3N3O3S |
| Molecular Weight | 531.59 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Adamantan Standards
- N-(adamantan-1-yl)-2-((3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 487032-04-2)
- N-(adamantan-1-yl)-3-amino-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 625369-55-3)
- 6-((2-(Adamantan-1-yl)-2-oxoethyl)thio)-4-(4-butoxy-3-methoxyphenyl)-2-imino-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 340817-99-4)
- n-(4-{[(adamantan-1-yl)formohydrazido]carbonyl}phenyl)-2,5-dichlorothiophene-3-sulfonamide (CAS 743450-66-0)
- N-(adamantan-1-yl)-4-(2-(3-(adamantan-1-yl)thioureido)ethyl)piperazine-1-carbothioamide (CAS 866038-34-8)
- Di(adamantan-1-yl)(2-(2-methoxynaphthalen-1-yl)phenyl)phosphineoxide (CAS 930807-42-4)
- Di(adamantan-1-yl)(2-((triisopropylsilyl)oxy)phenyl)phosphine (CAS 1384966-55-5)
- 2-{[6-(adamantan-1-yl)-3-cyanopyridin-2-yl]sulfanyl}-N-(6-nitro-1,3-benzothiazol-2-yl)acetamide (CAS 340817-92-7)
Recommended Standards
- 1-((11bS,12S,14aR)-13-Methoxy-2,3,5,6,11b,12-hexahydro-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-yl) 4-methyl (2R,3S)-2,3-dihydroxy-2-isopentylsuccinate (CAS 26833-86-3)
- Desmethyl homoharringtonine-d (CAS 98599-84-9)
- 3-(Cyclohexylmethyl)-8,9-dimethoxy-5-((2-(trifluoromethyl)benzyl)thio)imidazo[1,2-c]quinazolin-2(3H)-one (CAS 1031247-35-4)
- Fmoc-18-amino-4,7,10,13,16-pentaoxaoctadecanoic acid (CAS 882847-32-7)
- 6-(4-Chlorophenyl)-4-(methylthio)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 68192-59-6)
- Ethyl 3-amino-3-(4-isopropoxy-3-methoxyphenyl)propanoate (CAS 945451-04-7)
- 1-Propanethiol-SD (CAS 64071-73-4)
- 5-Methoxy-N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine (CAS 827031-23-2)
- 2-(1,3-Dioxoisoindolin-2-yl)acetonitrile (CAS 3842-20-4)
- 2-(4-Hydroxyphenyl)-1H-indene-1,3(2H)-dione (CAS 1217-32-9)
- 4-Chloro-5-nitro-2-phenylpyrimidine (CAS 184109-87-3)
- o-((5-Methylfuran-2-yl)methyl)hydroxylamine (CAS 1520742-21-5)
- 5-Chlorobenzo-2,1,3-thiadiazole (CAS 2207-32-1)
- [D-His1]-Semaglutide (CAS CATO-C4X-2226127)
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