n-(4-{[(adamantan-1-yl)formohydrazido]carbonyl}phenyl)-2,5-dichlorothiophene-3-sulfonamide CAS 743450-66-0
| CAS No. | 743450-66-0 |
| Molecular Formula | C22H23Cl2N3O4S2 |
| Molecular Weight | 528.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of n-(4-{[(adamantan-1-yl)formohydrazido]carbonyl}phenyl)-2,5-dichlorothiophene-3-sulfonamide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies n-(4-{[(adamantan-1-yl)formohydrazido]carbonyl}phenyl)-2,5-dichlorothiophene-3-sulfonamide (CAS 743450-66-0), a certified reference material (molecular formula C22H23Cl2N3O4S2, MW 528.47 g/mol) for analytical method development and quality control.
The molecular framework of n-(4-{[(adamantan-1-yl)formohydrazido]carbonyl}phenyl)-2,5-dichlorothiophene-3-sulfonamide (C22H23Cl2N3O4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures n-(4-{[(adamantan-1-yl)formohydrazido]carbonyl}phenyl)-2,5-dichlorothiophene-3-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H23Cl2N3O4S2 |
| Molecular Weight | 528.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related n Standards
- 6-((2-(Adamantan-1-yl)-2-oxoethyl)thio)-4-(4-butoxy-3-methoxyphenyl)-2-imino-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 340817-99-4)
- 6-(Adamantan-1-yl)-3-amino-N-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 488119-86-4)
- N-(adamantan-1-yl)-2-((3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 487032-04-2)
- N-(adamantan-1-yl)-3-amino-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 625369-55-3)
- N-(adamantan-1-yl)-4-(2-(3-(adamantan-1-yl)thioureido)ethyl)piperazine-1-carbothioamide (CAS 866038-34-8)
- Di(adamantan-1-yl)(2-(2-methoxynaphthalen-1-yl)phenyl)phosphineoxide (CAS 930807-42-4)
- Di(adamantan-1-yl)(2-((triisopropylsilyl)oxy)phenyl)phosphine (CAS 1384966-55-5)
- 2-{[6-(adamantan-1-yl)-3-cyanopyridin-2-yl]sulfanyl}-N-(6-nitro-1,3-benzothiazol-2-yl)acetamide (CAS 340817-92-7)
Recommended Standards
- DNP-PEG4-NHS ester (CAS 858126-78-0)
- Flomoxef Impurity 53 (CAS CATO-C4X-138253)
- Isopropyl ((((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1337529-49-3)
- 5-((3-(3-Bromo-4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(sec-butyl)-2-thioxothiazolidin-4-one (CAS 623933-23-3)
- 6-Methylpyridine-2,3-diamine dihydrochloride (CAS 77712-94-8)
- Ethyl (R)-1-Boc-3-pyrrolidinecarboxylate (CAS 1314419-65-2)
- 1-(3-Bromo-2-chloro-5-fluorophenyl)ethanone (CAS 2090978-28-0)
- 3-Benzyl-9-oxa-3,7-diazabicyclo[3.3.1]nonane dihydrochloride (CAS 335620-97-8)
- Benzo[1,2-b:3,4-b':5,6-b'']trithiophene-2,5,8-tricarboxylic acid (CAS 1174223-25-6)
- 4-(5,6-Dimethylbenzo[d]oxazol-2-yl)aniline (CAS 313549-30-3)
- Budesonide Impurity 28 (Mixture of Diastereomers) (CAS 2408495-96-3)
- Dimethyl 5-(m-tolyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate (CAS 339113-00-7)
- tert-Butyl 6-(aminomethyl)-2-azabicyclo[4.1.0]heptane-2-carboxylate (CAS 1504412-80-9)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
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