5-((2,2,2-Trifluoroethoxy)methyl)furan-2-carboxylic acid CAS 488795-29-5
| CAS No. | 488795-29-5 |
| Molecular Formula | C8H7F3O4 |
| Molecular Weight | 224.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-((2,2,2-Trifluoroethoxy)methyl)furan-2-carboxylic acid (CAS 488795-29-5) is a high-purity analytical reference standard with the molecular formula C8H7F3O4 and a molecular weight of 224.13 g/mol.
The molecular framework of 5-((2,2,2-Trifluoroethoxy)methyl)furan-2-carboxylic acid (C8H7F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-((2,2,2-Trifluoroethoxy)methyl)furan-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7F3O4 |
| Molecular Weight | 224.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Trifluoroethoxy Standards
- 1-[(2,2,2-trifluoroethoxy)methyl]-1h-pyrazole-3-carboxylic acid (CAS 1170070-40-2)
- 1-Methyl-3-(2,2,2-trifluoroethoxy)-1H-pyrazole-5-carboxylic acid (CAS 1227002-41-6)
- 1-Methyl-5-(2,2,2-trifluoroethoxy)-1H-pyrazole-4-carboxylic acid (CAS 1437482-19-3)
- 1-Methyl-5-(2,2,2-trifluoroethoxy)-1H-pyrazole-3-carboxylic acid (CAS 1477901-19-1)
- 1-(3-(2,2,2-Trifluoroethoxy)propyl)-1h-pyrazol-3-amine (CAS 1247114-07-3)
- 4-Methyl-1-(2-(2,2,2-trifluoroethoxy)ethyl)-1h-pyrazol-3-amine (CAS 1343246-40-1)
- 2-(2,2,2-Trifluoroethoxy)pyrimidin-4-amine (CAS 1199243-92-9)
- 5-(2,2,2-Trifluoroethoxy)pyrazine-2-carboxylic acid (CAS 1174323-36-4)
Recommended Standards
- 4,6-dichloro-2,3-dimethyl-2H-pyrazolo[4,3-c]pyridine (CAS 2088840-48-4)
- 5,6-Dinitro-1,3-dihydro-benzoimidazol-2-one (CAS 3705-86-0)
- 4,4,5,5-Tetramethyl-2-(5-methylthiophen-3-yl)-1,3,2-dioxaborolane (CAS 874959-74-7)
- 5,7-Dichloro-3-ethylpyrazolo[1,5-a]pyrimidine (CAS 779353-64-9)
- 2-Bromo-4-methyl-5-nitrophenol (CAS 103448-24-4)
- Vernakalant Impurity 4 (CAS 795282-28-9)
- XPhos Pd G2 (CAS 1310584-14-5)
- 1-(3-Bromobenzyl)azepane (CAS 414889-80-8)
- 1-Ethyl-4-(5-(1-ethylquinolin-4(1H)-ylidene)penta-1,3-dien-1-yl)quinolin-1-ium iodide (CAS 18300-31-7)
- Hex-5-en-2-amine (CAS 7380-76-9)
- 2-(3,5-Dichlorophenyl)butan-2-ol (CAS 76499-95-1)
- ((3aR,5R,6S,6aS)-6-Fluoro-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate (CAS 125291-12-5)
- N-(2-Morpholinoethyl)-6-phenylpyrimidin-4-amine (CAS 914217-63-3)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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