5-(3,4-Dichlorophenyl)-3-hydroxy-4-(4-methoxy-3-methylbenzoyl)-1-(2-morpholinoethyl)-1H-pyrrol-2(5H)-one CAS 489405-46-1
| CAS No. | 489405-46-1 |
| Molecular Formula | C25H26Cl2N2O5 |
| Molecular Weight | 505.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(3,4-Dichlorophenyl)-3-hydroxy-4-(4-methoxy-3-methylbenzoyl)-1-(2-morpholinoethyl)-1H-pyrrol-2(5H)-one (CAS 489405-46-1) is a high-purity analytical reference standard with the molecular formula C25H26Cl2N2O5 and a molecular weight of 505.39 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-(3,4-Dichlorophenyl)-3-hydroxy-4-(4-methoxy-3-methylbenzoyl)-1-(2-morpholinoethyl)-1H-pyrrol-2(5H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 505.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H26Cl2N2O5 |
| Molecular Weight | 505.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 4-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrophenyl}-2-(4-chlorophenyl)-1,3-thiazole (CAS 262439-68-9)
- Ethyl 3-(2-chloro-6-fluorophenyl)-2-(2-((3-chlorobenzyl)thio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)propanoate (CAS 477860-57-4)
- (S)-1-((S)-2-amino-3,3-dimethylbutanoyl)-N-(4-iodophenyl)-N-phenylpyrrolidine-2-carboxamide (CAS 371919-42-5)
- rac-Monepantel Sulfone (CAS 851976-52-8)
- 4-(Pyrazin-2-yl)but-3-yn-1-ol (CAS 873324-93-7)
- 3,4-Dimethyl-2-hexanone (CAS 19550-10-8)
- 2-(4-Fluoropyridin-2-yl)ethan-1-amine (CAS 1000554-27-7)
- Azilsartan Impurity 18 (CAS 2171316-29-1)
- Crisaborole lmpurity 81 (CAS CATO-C4X-202181)
- N-(thiazol-2-yl)-1H-benzo[d][1,2,3]triazole-1-carbothioamide (CAS 690634-07-2)
- 2-(5-methylfuran-2-yl)ethan-1-ol (CAS 35942-94-0)
- Vazegepant Impurity 12 (CAS CATO-C4X-320012)
- 1-(1-Bromobutan-2-yl)-4-fluorobenzene (CAS 7054-62-8)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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