1-Benzyl-3-(4-chlorobenzyl)piperazine CAS 489437-81-2
| CAS No. | 489437-81-2 |
| Molecular Formula | C18H21ClN2 |
| Molecular Weight | 300.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1-Benzyl-3-(4-chlorobenzyl)piperazine (CAS 489437-81-2), a certified reference material (molecular formula C18H21ClN2, MW 300.83 g/mol) for analytical method development and quality control.
Structurally, 1-Benzyl-3-(4-chlorobenzyl)piperazine (C18H21ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 300.83 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H21ClN2 |
| Molecular Weight | 300.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Benzyl Standards
- 2-((3-Chlorobenzyl)thio)-1-phenyl-1H-imidazole (CAS 478046-10-5)
- (E)-1-(3-chlorobenzyl)-3-(4-methylstyryl)urea (CAS 339278-61-4)
- 2-(4-Chlorobenzyl)-6-methoxy-3,4-dihydronaphthalen-1(2H)-one (CAS 62085-82-9)
- N-(2-Chlorobenzyl)-5-methylfuro[3,2-b]pyridine-2-carboxamide (CAS 941928-12-7)
- 4-((3-Chlorobenzyl)oxy)-1H-indole-2-carboxylic acid (CAS 1215609-58-7)
- 2-((4-Chlorobenzyl)oxy)isoquinoline-1,3(2H,4H)-dione (CAS 320420-22-2)
- 3-(4-Chlorobenzyl)-6-fluoro-2-methoxyquinoline (CAS 1355229-67-2)
- 5-(3-Chlorobenzyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 791717-23-2)
Recommended Standards
- 1-[(4-Chlorophenyl)(phenyl)methyl]-1,4-diazepane (CAS 24342-60-7)
- 5-((4-Benzylpiperidin-1-yl)methyl)-2-chloropyridine (CAS 861207-53-6)
- (R)-1-benzyl-3-(4-chlorobenzyl)piperazine (CAS 276861-71-3)
- 6-benzyl-2-chloro-8-isopropyl-7,8-dihydro-5H-1,6-naphthyridine (CAS 2758498-35-8)
- Rac-(1r,2s)-2-(trifluoromethyl)cyclopropan-1-amine hydrochloride (CAS 1258640-83-3)
- TERT-BUTYL 4-(2-AMINO-4-BROMOBENZOYL)PIPERAZINE-1-CARBOXYLATE (CAS 1464158-03-9)
- 2-Methoxy-5-(piperazin-1-ylmethyl)phenol (CAS 478171-73-2)
- 3-Methoxy-1-methyl-1H-indazol-5-amine (CAS 1354225-63-0)
- Ozenoxacin Impurity 86 (CAS CATO-C4X-279686)
- 3-(Trifluoromethylthio) isonicotinonitrile (CAS 1204235-20-0)
- Porphobilinogen-13C3DISCONTINUED. Please see P689504 (CAS 1246820-69-8)
- 2,3-Dihydro-imidazo[1,2-α]pyridine HBr (CAS 38772-14-4)
- 4-(4-Fluorophenyl)-4'-pentyl-1,1'-bi(cyclohexane) (CAS 82832-29-9)
- Hexapeptide-9 (CAS 1228371-11-6)
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