Norepinephrine Impurity 21 CAS 490-89-1
| CAS No. | 490-89-1 |
| Molecular Formula | C8H7NO3 |
| Molecular Weight | 165.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Norepinephrine Impurity 21.
As a process- or degradation-related impurity, Norepinephrine Impurity 21 (CAS 490-89-1, C8H7NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H7NO3, Norepinephrine Impurity 21 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 165.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Norepinephrine Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7NO3 |
| Molecular Weight | 165.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 28 (CAS 117883-03-1)
- Norepinephrine Impurity 40 (CAS 3569-19-5)
- Norepinephrine Impurity 95 (CAS CATO-C4X-151495)
- Norepinephrine Impurity 15 (CAS 29477-55-2)
- Norepinephrine Impurity 27 (CAS 14309-96-7)
- Norepinephrine Impurity 127 (CAS 94593-04-1)
- Norepinephrine Impurity 20 (CAS 67896-55-3)
- Norepinephrine impurity 152 (CAS 490-90-4)
Recommended Standards
- N-Nitroso Azelastine EP Impurity A (CAS CATO-C4X-139640)
- N-(5-Formyl-2-hydroxyphenyl)formamide (CAS 903563-43-9)
- Rtitrexed Impurity 25 (CAS CATO-C4X-138625)
- 5-Hydroxy-6-methylpyridine-3,4-dicarbaldehyde (CAS 19099-89-9)
- Urapidil Impurity 14 (CAS 6972-27-6)
- Eltrombopag impurity 149 (CAS CATO-C4X-1198149)
- Ibuprofen Impurity 153 (CAS CATO-C4X-1082153)
- N-ethylcyclobutanamine (CAS 852108-24-8)
- 1-[(4-Chlorophenyl)methyl]-3-nitro-1h-pyrazole (CAS 957478-22-7)
- S-Adenosyl-L-Methionine Impurity 19 (CAS 13484-65-6)
- 2-(Difluoromethyl)-3,6-dihydroxypyridine-4-carbonyl chloride (CAS 1805290-51-0)
- (1S)-6,6'-Dioctyl[1,1'-binaphthalene]-2,2'-diol (CAS 1154061-89-8)
- 2,3,4,9-tetrahydro-1H-carbazol-6-amine hydrochloride (CAS 1079-26-1)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com