(6-Chloropyridin-3-yl)(2,6-difluorophenyl)methanone CAS 490038-59-0
| CAS No. | 490038-59-0 |
| Molecular Formula | C12H6ClF2NO |
| Molecular Weight | 253.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (6-Chloropyridin-3-yl)(2,6-difluorophenyl)methanone is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (6-Chloropyridin-3-yl)(2,6-difluorophenyl)methanone (CAS 490038-59-0), a certified reference material (molecular formula C12H6ClF2NO, MW 253.63 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H6ClF2NO, (6-Chloropyridin-3-yl)(2,6-difluorophenyl)methanone contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 253.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (6-Chloropyridin-3-yl)(2,6-difluorophenyl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H6ClF2NO |
| Molecular Weight | 253.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloropyridin Standards
- (6-Chloropyridin-3-yl)(3,4-difluorophenyl)methanone (CAS 1187169-69-2)
- 1-(3-Chloropyridin-2-yl)-3-methoxy-1h-pyrazole-5-carboxylic acid (CAS 1122021-75-3)
- Ethyl 3-(2-chloropyridin-4-yl)-1,2,4-oxadiazole-5-carboxylate (CAS 1219571-90-0)
- 3-(3-(2-Chloropyridin-4-yl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 1255099-24-1)
- Ethyl 3-(2-chloropyridin-3-yl)-1,2,4-oxadiazole-5-carboxylate (CAS 890095-91-7)
- 1-(6-Chloropyridin-2-yl)-N-methyl-4-nitro-1H-pyrazol-5-amine (CAS 318238-09-4)
- 3-[(6-chloropyridin-3-yl)methyl]-5,5-dimethylimidazolidine-2,4-dione (CAS 1016720-44-7)
- 1-(2-((5-Chloropyridin-2-yl)amino)thiazol-5-yl)ethan-1-one (CAS 952183-72-1)
Recommended Standards
- Trichloro(3-phenylpropyl)silane (CAS 13617-40-8)
- 2-Chloro-1-isocyanato-4-trifluoromethylsulfanyl-benzene (CAS 55225-89-3)
- 2-Chloro-6-(trifluoromethoxy)benzothiazole (CAS 133840-96-7)
- 2-Chloro-4-isocyanato-1-[(trifluoromethyl)-thio]benzene (CAS 76729-41-4)
- 5-(4-Chlorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 88466-67-5)
- Ethyl 5-aminobicyclo[3.2.1]Octane-1-carboxylate (CAS 1383973-47-4)
- tert-Butyl 2-hydroxy-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate (CAS 189149-23-3)
- N(1),N(12)-Diethylspermine-d10 4HCl (CAS 113812-15-0)
- 3,4-Dibromo-2-(((2-(3-chlorophenyl)benzo[d]oxazol-5-yl)imino)methyl)-6-methoxyphenol (CAS 330564-04-0)
- 2-(3,5-Dimethoxyphenoxy)ethanol (CAS 27318-86-1)
- 5-Bromo-1-isobutyl-1H-1,2,3-triazole (CAS 1393559-99-3)
- N-(2-(4-Bromo-2-fluorophenoxy)ethyl)cyclohexanamine (CAS 1283004-33-0)
- 2-(2-Fluorophenyl)ethanimidamide hydrochloride (CAS 860815-04-9)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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