Methyl 2-hydroxy-[1,1'-biphenyl]-3-carboxylate CAS 4906-69-8
| CAS No. | 4906-69-8 |
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 2-hydroxy-[1,1'-biphenyl]-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 2-hydroxy-[1,1'-biphenyl]-3-carboxylate (CAS 4906-69-8), molecular formula C14H12O3 and molecular weight 228.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 2-hydroxy-[1,1'-biphenyl]-3-carboxylate (C14H12O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Methyl Standards
- 3-Hydroxy-4'-methoxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 1014625-93-4)
- 2-Hydroxy-5-methylphenyl benzoate (CAS 10268-64-1)
- 4-Hydroxy-4'-(hydroxymethyl)-[1,1'-biphenyl]-3-carbaldehyde (CAS 1098984-09-8)
- 2'-Hydroxy-2-methyl-[1,1'-biphenyl]-4-carboxylic acid (CAS 1141473-81-5)
- Methyl 3-hydroxy-[1,1'-biphenyl]-4-carboxylate (CAS 117369-94-5)
- 2-(4'-Hydroxy-[1,1'-biphenyl]-2-yl)acetic acid (CAS 1176610-22-2)
- Ethyl 8-hydroxy-1,4-dioxaspiro[4.5]Dec-7-ene-7-carboxylate (CAS 121210-56-8)
- 5-Hydroxy-4'-methyl-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261978-76-0)
Recommended Standards
- Methyl 2'-hydroxy-[1,1'-biphenyl]-3-carboxylate (CAS 92254-28-9)
- Methyl 2-hydroxy-[1,1'-biphenyl]-4-carboxylate (CAS 198994-00-2)
- Methyl 2′-hydroxy[1,1′-biphenyl]-4-carboxylate (CAS 40501-40-4)
- Methyl 2-phenoxybenzoate (CAS 21905-56-6)
- 2-(tert-Butoxy)-4-iodophenol (CAS 1243326-70-6)
- tert-Butyl 5-formyl-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 1363210-19-8)
- 1082040-64-9 1h-indazole-3-carboxylic acid,5-hydroxy-,methyl ester (CAS 1082040-64-9)
- 2-Amino-3-methyl-N-(5-methylthiazol-2-yl)butanamide (CAS 1105643-52-4)
- 1261970-42-6 2'-Fluoro-4'-methyl-5-nitro-[1,1'-biphenyl]-3-carboxylic acid 3360AD C14H10FNO4 (CAS 1261970-42-6)
- 4-(benzyloxy)-3-bromoaniline hydrochloride (CAS 215113-01-2)
- 3-[(tert-butyldimethylsilyl)oxy]-3-cyclohexylbutanal (CAS 2044927-01-5)
- Methyl N-(2,5-dimethylphenyl)-N-tosylglycinate (CAS 333454-38-9)
- 5-(2,4-Dichlorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole (CAS 694521-58-9)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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