N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide CAS 491867-82-4
| CAS No. | 491867-82-4 |
| Molecular Formula | C19H20FN3O3 |
| Molecular Weight | 357.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide.
N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide (CAS 491867-82-4), molecular formula C19H20FN3O3 and molecular weight 357.38 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 357.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H20FN3O3 |
| Molecular Weight | 357.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 1-(Benzo[d][1,3]dioxol-5-yl)-5-((pyrimidin-2-ylthio)methyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1416346-84-3)
- (Z)-2-(Benzo[d]thiazol-2-yl)-3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one (CAS 327091-55-4)
- 2-(4-((1H-Benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)-N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 1171202-96-2)
- 2-(Benzo[d]thiazol-2-ylthio)-N'-(3-(furan-2-yl)-2-methylallylidene)acetohydrazide (CAS 308096-05-1)
- 2-(1H-Benzo[d]imidazol-1-yl)-1-(7-(thiophen-2-yl)-1,4-thiazepan-4-yl)ethan-1-one (CAS 1705067-81-7)
- N-((1-(Benzo[d]thiazol-2-yl)piperidin-4-yl)methyl)thiophene-3-carboxamide (CAS 1797218-47-3)
- 2-(1H-Benzo[d]imidazol-2-yl)-N'-(4-bromobenzylidene)acetohydrazide (CAS 539806-78-5)
- (4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(4-chlorophenyl)methanone (CAS 309290-28-6)
Recommended Standards
- N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-(4-fluorophenyl)piperazine-1-carboxamide (CAS 865659-74-1)
- Raltitrexed Impurity 11 (CAS 651295-42-0)
- N-(1,3-Diphenyl-1H-pyrazol-5-yl)-4-fluorobenzamide (CAS 781652-51-5)
- Trelagliptin Impurity 22 (CAS 865759-25-7)
- Davy Reagent Methyl (CAS 82737-61-9)
- 2-(4-Chlorophenyl)-2-(pyrrolidin-1-yl)ethan-1-amine oxalate (CAS 1185303-43-8)
- Ethyl 4-(2-aminobenzoyl)piperazine-1-carboxylate (CAS 925052-31-9)
- Defluoro Paroxetine (CAS 1322626-23-2)
- cis-2,6-Dimethylmorpholine (CAS 6485-55-8)
- 2-Fluoro-4-isopropylbenzonitrile (CAS 1369834-93-4)
- Ethyl 4-acetyl-2-aminopyrimidine-5-carboxylate (CAS 62328-06-7)
- 6-Chloro-5-(difluoromethyl)-2-methoxypyridine-3-sulfonamide (CAS 1806901-01-8)
- 3-Chloro-N-[2-methyl-2-(methylsulfanyl)propyl]-5-(trifluoromethyl)pyridin-2-amine (CAS 338954-37-3)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com