Metixene Hydrochloride EP Impurity B CAS 492-22-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.492-22-8
Molecular FormulaC13H8OS
Molecular Weight212.27 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Metixene Hydrochloride EP Impurity B CAS 492-22-8 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Metixene Hydrochloride EP Impurity B (CAS 492-22-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H8OS and a molecular weight of 212.27 g/mol.

Based on its molecular formula C13H8OS, Metixene Hydrochloride EP Impurity B contains sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 212.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC13H8OS
Molecular Weight212.27 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Sulfur Atoms1

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