2,5-Dihydroxynaphthalene-1,4-dione CAS 4923-55-1
| CAS No. | 4923-55-1 |
| Molecular Formula | C10H6O4 |
| Molecular Weight | 190.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,5-Dihydroxynaphthalene-1,4-dione (CAS 4923-55-1), molecular formula C10H6O4 and molecular weight 190.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,5-Dihydroxynaphthalene-1,4-dione (C10H6O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6O4 |
| Molecular Weight | 190.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Dihydroxynaphthalene Standards
- 2,3-Dihydroxynaphthalene-1,4-dione (CAS 605-37-8)
- 2,6-Dihydroxynaphthalene-1,4-dione (CAS 31039-62-0)
- 2,7-Dihydroxynaphthalene-1,4-dione (CAS 31039-63-1)
- 2,8-Dihydroxynaphthalene-1,4-dione (CAS 4923-58-4)
- 2,7-Dihydroxynaphthalene-1-carbaldehyde (CAS 20258-95-1)
- 5,8-Dihydroxynaphthalene-1,4(4aH,8aH)-dione (CAS 887574-80-3)
- 1,4-dihydroxynaphthalene monomethyl ether 1-hydroxy-4-methoxynaphthalene 4-Methoxy-1-naphthol 4-methoxy-naphthalen-1-ol 4-methoxynaphthalen-1-ol 84-85-5 (CAS 84-85-5)
- 1,8-dihydroxynaphthalene-2-carbaldehyde (CAS 858457-19-9)
Recommended Standards
- 2,3-Diacetoxypropanoic acid (CAS 87844-87-9)
- 2,2'-(1,4-Phenylene)bis(2-oxoacetaldehyde) (CAS 2673-16-7)
- 2,2'-(1,3-Dioxolane-2,2-diyl)diacetic acid (CAS 5694-91-7)
- 2-[3-(difluoromethyl)-5-methyl-1h-pyrazol-1-yl]acetic acid (CAS 957487-29-5)
- 3-(4-Methyl-1H-benzo[d]imidazol-1-yl)butanenitrile (CAS 172839-53-1)
- 3-(4,5-Dihydro-4-phenyl-5-thioxo-1H-1,2,4-triazol-3-yl)-N,N-diethylbenzenesulfonamide (CAS 438021-60-4)
- 6-Chloro-5-(difluoromethyl)pyridin-2-amine (CAS 1441636-27-6)
- (R)-3-((tert-Butyldimethylsilyl)oxy)pyrrolidin-2-one (CAS 1351501-16-0)
- 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 190954-81-5)
- 2-(5-Bromothiophen-2-yl)furan (CAS 91891-82-6)
- 2-Chloro-5-(methoxymethyl)aniline (CAS 1097797-19-7)
- 4-Amino-3,5-dimethylbenzamide (CAS 103796-44-7)
- 1,4-Bis(4-fluorobenzyl)-1,4-diazepane (CAS 132481-39-1)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
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