Esomeprazole Impurity 78 CAS 49559-83-3
| CAS No. | 49559-83-3 |
| Molecular Formula | C8H7NO2S |
| Molecular Weight | 181.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Esomeprazole Impurity 78 (C8H7NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Esomeprazole Impurity 78 (CAS 49559-83-3) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7NO2S and a molecular weight of 181.21 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Esomeprazole Impurity 78 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7NO2S |
| Molecular Weight | 181.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Esomeprazole Standards
- Esomeprazole Impurity 109 (CAS 86604-79-7)
- Esomeprazole Impurity 48 (CAS CATO-C4X-111248)
- Esomeprazole Impurity 84 (CAS 149082-03-1)
- Esomeprazole Impurity 43 (CAS 149367-83-9)
- Esomeprazole Impurity 86 (CAS 287118-45-0)
- Esomeprazole Impurity 15 (CAS 208-75-3)
- Esomeprazole Impurity 82 (CAS 206990-64-9)
- Esomeprazole Impurity 101 (CAS 84006-10-0)
Recommended Standards
- Linezolid Impurity 97 (CAS 384344-17-6)
- Ilaprazole impurity 185 (CAS CATO-C4X-1130185)
- DL-Methionine Sulfone (CAS 820-10-0)
- Ilaprazole Impurity 54 (CAS CATO-C4X-113054)
- Peramivir Impurity 128 (CAS CATO-C4X-1833128)
- Linagliptin Impurity 17 (CAS 6140-11-0)
- Valsartan Impurity 71 (CAS CATO-C4X-105771)
- Ethyl 2-(4-chlorophenyl)-2-(piperazin-1-yl)acetate (CAS 877977-12-3)
- {4-[2-(4-Benzylpiperazino)ethoxy]phenyl}methanol (CAS 937604-12-1)
- 2-(2,2,2-Trifluoroethyl)-3H-imidazo[4,5-c]pyridine (CAS 1211592-76-5)
- 1-Boc-3-iodo-6-phenyl-5-azaindole (CAS 1448259-12-8)
- N-(4-Ethyl-2-(ethylthio)-4-methyl-4H-imidazol-5-yl)hydroxylamine (CAS 330601-26-8)
- 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl 1-methylcyclopropanecarboxylate (CAS 2240185-64-0)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
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