3-Amino-6-(pyridin-4-yl)-N-[2-(trifluoromethyl)phenyl]thieno[2,3-b]pyridine-2-carboxamide CAS 496019-29-5
| CAS No. | 496019-29-5 |
| Molecular Formula | C20H13F3N4OS |
| Molecular Weight | 414.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-6-(pyridin-4-yl)-N-[2-(trifluoromethyl)phenyl]thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-29-5) is a high-purity analytical reference standard with the molecular formula C20H13F3N4OS and a molecular weight of 414.40 g/mol.
The molecular framework of 3-Amino-6-(pyridin-4-yl)-N-[2-(trifluoromethyl)phenyl]thieno[2,3-b]pyridine-2-carboxamide (C20H13F3N4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Amino-6-(pyridin-4-yl)-N-[2-(trifluoromethyl)phenyl]thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H13F3N4OS |
| Molecular Weight | 414.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-6-benzyl-7-methyl-4-(3-nitrophenyl)-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile (CAS 265315-71-7)
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Recommended Standards
- 2-(2-Cyanobenzenesulfinyl)-N-[3-(trifluoromethyl)phenyl]benzamide (CAS 477710-69-3)
- 6-(Furan-2-yl)-2-(((6-methyl-1H-benzo[d]imidazol-2-yl)methyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 723748-19-4)
- 2-((4-Fluorobenzyl)thio)-5-(1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)-1,3,4-oxadiazole (CAS 478080-24-9)
- Methyl 2-({3-cyano-4-[3-(trifluoromethyl)phenyl]pyridin-2-yl}sulfanyl)benzoate (CAS 478245-75-9)
- 3’-Hydroxy-4’-methoxyflavanone (CAS 1621-70-1)
- 9-Bromoanthracene-d9 (CAS 183486-02-4)
- 3-(1H-Pyrrol-1-yl)isoxazole (CAS 383142-47-0)
- 4-(Azetidin-3-yl)pyrimidine 2HCl (CAS 1384264-47-4)
- Methyl 4-bromo-6-(chloromethyl)picolinate (CAS 1393568-72-3)
- 3-(3-Chloro-2,6-dimethylbenzenesulfonyl)-4,6-dimethyl-1,2-dihydropyridin-2-one (CAS 860787-62-8)
- 4-BRomo-2-nitrophenoxyacetic acid (CAS 128627-49-6)
- O-(Cyclopropylmethyl)hydroxylamine (CAS 75647-90-4)
- 2-(2-Chloroethyl)-1H-isoindole-1,3-dione (CAS 6270-06-0)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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