4-(2-Fluorophenyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide CAS 496776-80-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Fluorophenyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide.

4-(2-Fluorophenyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide (CAS 496776-80-8), molecular formula C18H20FN3OS and molecular weight 345.43 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, 4-(2-Fluorophenyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 345.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(2-Fluorophenyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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