496794-70-8 N-(4-chloro-3-(6-(dimethylamino)-1H-benzo[d]imidazol-2-yl)phenyl)-3,5-dimethoxybenzamide Stemolecule SMO Antagonist CAS 496794-70-8
| CAS No. | 496794-70-8 |
| Molecular Formula | C24H23ClN4O3 |
| Molecular Weight | 450.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 496794-70-8 N-(4-chloro-3-(6-(dimethylamino)-1H-benzo[d]imidazol-2-yl)phenyl)-3,5-dimethoxybenzamide Stemolecule SMO Antagonist (C24H23ClN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 496794-70-8 N-(4-chloro-3-(6-(dimethylamino)-1H-benzo[d]imidazol-2-yl)phenyl)-3,5-dimethoxybenzamide Stemolecule SMO Antagonist (CAS 496794-70-8), a certified reference material (molecular formula C24H23ClN4O3, MW 450.92 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H23ClN4O3 |
| Molecular Weight | 450.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- (6-Bromo-2-(difluoromethyl)-5-nitropyridin-3-yl)methanol (CAS 1806857-51-1)
- 2-Amino-5-benzyloxybenzoic acid (CAS 58662-78-5)
- 2-{[(2-Chloro-acetyl)-isopropyl-amino]-methyl}-pyrrolidine-1-carboxylic acid benzyl ester (CAS 1353956-20-3)
- (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(diethoxyphosphoryl)phenyl)propanoic acid (CAS 154483-81-5)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-iodo-5-methylpyridine (CAS 1805534-64-8)
- Benzyl 3-chloro-4-cyano-5,6,7,9-tetrahydro-8H-pyrido[3,4-c]azepine-8-carboxylate (CAS 1341039-99-3)
- 3-Cyclopropoxy-4-iodobenzamide (CAS 1243321-52-9)
- 141801-03-8 IL-1 Receptor Peptide (human) (CAS 141801-03-8)
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