Olaparib Impurity 118 CAS CATO-C4X-1135118
| CAS No. | CATO-C4X-1135118 |
| Molecular Formula | C24H23ClN4O3 |
| Molecular Weight | 450.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 450.92 g/mol gives Olaparib Impurity 118 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Olaparib Impurity 118 (CAS CATO-C4X-1135118), a pharmacopoeial impurity reference standard (molecular formula C24H23ClN4O3, MW 450.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Olaparib Impurity 118 (C24H23ClN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Olaparib Impurity 118 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23ClN4O3 |
| Molecular Weight | 450.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib Impurity 160 (CAS CATO-C4X-1135160)
- Olaparib Impurity 10 (CAS CATO-C4X-113510)
- Olaparib Impurity 120 (CAS CATO-C4X-1135120)
- Olaparib Impurity 21 (CAS CATO-C4X-1135121)
- Olaparib Impurity 151 (CAS CATO-C4X-1135151)
- Olaparib Impurity 163 (CAS 1460272-52-9)
- Olaparib Impurity 9 (CAS CATO-C4X-11359)
- Olaparib Impurity 83 (CAS CATO-C4X-113583)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com