N-(3,4-dimethoxyphenethyl)-4-(trifluoromethyl)benzamide CAS 497060-02-3
| CAS No. | 497060-02-3 |
| Molecular Formula | C18H18F3NO3 |
| Molecular Weight | 353.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-(3,4-dimethoxyphenethyl)-4-(trifluoromethyl)benzamide (CAS 497060-02-3), a certified reference material (molecular formula C18H18F3NO3, MW 353.34 g/mol) for analytical method development and quality control.
N-(3,4-dimethoxyphenethyl)-4-(trifluoromethyl)benzamide (C18H18F3NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), N-(3,4-dimethoxyphenethyl)-4-(trifluoromethyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18F3NO3 |
| Molecular Weight | 353.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(3,4-dimethoxyphenethyl)-1-phenylcyclopentane-1-carboxamide (CAS 151156-92-2)
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- N-(3,4-dimethoxyphenethyl)-2-(1H-indol-3-yl)-2-oxoacetamide (CAS 140677-17-4)
- 5-((3,4-Dimethoxyphenethyl)amino)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 376605-33-3)
- 2-(1-((3,4-Dimethoxyphenethyl)amino)ethylidene)-1H-indene-1,3(2H)-dione (CAS 355430-61-4)
- 5-(((3,4-Dimethoxyphenethyl)amino)methyl)-1,3-dimethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 881450-50-6)
- Methyl 2-[1-(3,4-dimethoxyphenethyl)-4-hydroxy-2-oxo-1,2-dihydro-3-pyridinyl]acetate (CAS 478079-16-2)
- 2-(3,4-Dimethoxyphenethyl)-1-oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 77960-26-0)
Recommended Standards
- N-(2-(1H-pyrrol-1-yl)-5-(trifluoromethyl)phenyl)-2-morpholinoacetamide (CAS 866010-81-3)
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- N-((1-Cyclohexyl-1H-tetrazol-5-yl)methyl)-2-(trifluoromethyl)benzamide (CAS 920439-56-1)
- N-(Trimethylsilyl)bis(trifluoromethanesulfonyl)imide (CAS 82113-66-4)
- N'-(3,4-difluorobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 457607-49-7)
- 4-Ethyl-6-fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1243405-24-4)
- 8-Fluoro-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 1269531-27-2)
- (E)-3-chloro-N-(2-nitro-2-(phenylsulfonyl)vinyl)aniline (CAS 338407-51-5)
- tert-Butyl 6-iodo-3,4-dihydroisoquinoline-2(1h)-carboxylate (CAS 1008517-84-7)
- Methyl 5-Amino-3-fluoropyridine-2-carboxylate (CAS 1374652-08-0)
- 2-(2-(Methylsulfonyloxy)ethyl)-4-nitrobenzyl (methanesulfonate) (CAS 199014-22-7)
- 3-Cyano-n-(prop-2-yn-1-yl)benzamide (CAS 1017048-13-3)
- 5-(4-Chlorophenyl)-1-methyl-1H-pyrrole-2-carbaldehyde (CAS 824961-53-7)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
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