N-(5-Bromo-4,6-dimethylpyrimidin-2-yl)thiophene-2-carboxamide CAS 497060-01-2

Purity 97%+In StockPharmaceutical Standards
CAS No.497060-01-2
Molecular FormulaC11H10BrN3OS
Molecular Weight312.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-Bromo-4,6-dimethylpyrimidin-2-yl)thiophene-2-carboxamide CAS 497060-01-2 chemical structure

Description

The occurrence of N-(5-Bromo-4,6-dimethylpyrimidin-2-yl)thiophene-2-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(5-Bromo-4,6-dimethylpyrimidin-2-yl)thiophene-2-carboxamide (CAS 497060-01-2), molecular formula C11H10BrN3OS and molecular weight 312.19 g/mol, is a CATO reference standard with documented purity and traceability.

N-(5-Bromo-4,6-dimethylpyrimidin-2-yl)thiophene-2-carboxamide (C11H10BrN3OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(5-Bromo-4,6-dimethylpyrimidin-2-yl)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H10BrN3OS
Molecular Weight312.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentBr-containing
Nitrogen Atoms3
Sulfur Atoms1

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