TPPB CAS 497259-23-1
| CAS No. | 497259-23-1 |
| Molecular Formula | C27H30F3N3O3 |
| Molecular Weight | 501.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of TPPB is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
TPPB (CAS 497259-23-1), molecular formula C27H30F3N3O3 and molecular weight 501.54 g/mol, is a CATO reference standard with documented purity and traceability.
TPPB (C27H30F3N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), TPPB meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H30F3N3O3 |
| Molecular Weight | 501.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- U-68415 (CAS 104713-40-8)
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- 5-Bromo-6-cyclobutoxypyridin-3-amine (CAS 1524250-48-3)
- N-methyl-3-nitrobenzamide (CAS 3400-26-8)
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- Bis(3-chloro-4-fluorophenyl)(hydroxy)borane (CAS 872495-46-0)
- 3-(benzylsulfonyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide (CAS 1164476-67-8)
- 1-(4-((2-Aminoethyl)(cyclopropyl)amino)piperidin-1-yl)ethanone (CAS 1353944-64-5)
- 1,3,7-trimethyl-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione (CAS 39930-51-3)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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