alpha-(Trifluoromethyl)-6-methoxynaphthalene-2-methanol CAS 497937-74-3
| CAS No. | 497937-74-3 |
| Molecular Formula | C13H11F3O2 |
| Molecular Weight | 256.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of alpha-(Trifluoromethyl)-6-methoxynaphthalene-2-methanol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies alpha-(Trifluoromethyl)-6-methoxynaphthalene-2-methanol (CAS 497937-74-3), a certified reference material (molecular formula C13H11F3O2, MW 256.22 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, alpha-(Trifluoromethyl)-6-methoxynaphthalene-2-methanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 256.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), alpha-(Trifluoromethyl)-6-methoxynaphthalene-2-methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11F3O2 |
| Molecular Weight | 256.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related alpha Standards
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- 2-((6-(Trifluoromethyl)quinolin-4-yl)amino)ethan-1-ol (CAS 1065076-16-5)
- 1-(1-Ethyl-5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)ethan-1-one (CAS 1312137-42-0)
- 5-(3-(Trifluoromethyl)phenyl)cyclohexane-1,3-dione (CAS 144128-67-6)
- (2-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)phenyl)methanol (CAS 892502-29-3)
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Recommended Standards
- 9-(4-Nitrophenyl)-9H-purin-6-amine (CAS 21314-05-6)
- ethyl 5-(2,2,2-trifluoro-1,1-dimethyl-ethyl)-1,2,4-oxadiazole-3-carboxylate (CAS 2736511-26-3)
- 9-(3-Nitrophenyl)-9H-purin-6-amine (CAS 5356-52-5)
- Methyl 7-amino-3-cyano-2-(cyanomethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 886361-35-9)
- 4-Chloro-5-((3-methylbenzyl)oxy)-2-propylpyridazin-3(2H)-one (CAS 88094-06-8)
- 1-(5-Bromopyridin-2-yl)cyclopropan-1-ol (CAS 1335054-90-4)
- 4-(4-Methoxyphenyl)-5-[(Z)-2-(4-methoxyphenyl)diazen-1-yl]-2-phenylpyrimidine (CAS 339279-52-6)
- 2-Fluoro-3-(3-(trifluoromethoxy)phenyl)pyridine (CAS 1261725-31-8)
- 4-(Aminomethyl)-5-methyl-2,4-dihydro-3h-pyrazol-3-one dihydrochloride (CAS 1609406-66-7)
- 3-Isobutylpyrrolidine hydrochloride (CAS 959238-03-0)
- 1,4-Dichloro-2-iodo-3-methoxybenzene (CAS 873980-99-5)
- 2-(3-Fluoro-4-((methylsulfonyl)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1351499-67-6)
- Eltrombopag Impurity 113 (CAS CATO-C4X-1198113)
- Mast Cell Degranulating (MCD) Peptide HR-2 (CAS 80388-04-1)
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