4-[(tert-Butylamino)methyl]-2-methoxyphenol CAS 498577-18-7
| CAS No. | 498577-18-7 |
| Molecular Formula | C12H19NO2 |
| Molecular Weight | 209.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[(tert-Butylamino)methyl]-2-methoxyphenol is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[(tert-Butylamino)methyl]-2-methoxyphenol (CAS 498577-18-7), molecular formula C12H19NO2 and molecular weight 209.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(tert-Butylamino)methyl]-2-methoxyphenol (C12H19NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H19NO2 |
| Molecular Weight | 209.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related tert Standards
- 5-[(Butylamino)methyl]-2-methoxyphenol (CAS 1019489-94-1)
- 2-((Butylamino)methyl)-6-methoxyphenol (CAS 1019566-16-5)
- 2-((Sec-butylamino)methyl)-6-methoxyphenol (CAS 1019605-18-5)
- 2-((Sec-butylamino)methyl)-4-methoxyphenol (CAS 1038231-69-4)
- 2-((Butylamino)methyl)-4-methoxyphenol (CAS 1038259-06-1)
- 2-((Tert-butylamino)methyl)-4-methoxyphenol (CAS 1042523-55-6)
- 4-[(Butylamino)methyl]-2-methoxyphenol (CAS 112520-76-0)
- 2-((Butylamino)methyl)-5-methoxyphenol (CAS 1247174-22-6)
Recommended Standards
- 4-(3-Methoxy-3-methyl-butoxy)-phenylamine (CAS 883545-65-1)
- 4-Amino-5-(3-methoxyphenyl)pentan-1-ol (CAS 82590-42-9)
- 4-(3,4-Dimethoxyphenyl)butan-1-amine (CAS 74027-78-4)
- 4-Methyl-2-(2-propoxyethoxy)aniline (CAS 946683-32-5)
- Tert-butyl (5-formylbicyclo[3.1.1]Heptan-1-yl)carbamate (CAS 2375178-76-8)
- 8-Ethyl-1,2,3,4-tetrahydroquinoline (CAS 103858-38-4)
- 62649-23-4 Poly(Acrylamide), Carboxyl Modif, Low Carbox.Content, CA.MW 200000, Pure (CAS 62649-23-4)
- Methyl 6-cyano-1-methylpyrrolo[3,2-b]pyridine-2-carboxylate (CAS 952182-34-2)
- tert-Butyl 2-(1-hydroxyethyl)pyrrolidine-1-carboxylate (CAS 916145-68-1)
- 5-Bromo-N,4-dimethylnicotinamide (CAS 2246722-11-0)
- Letermovir Impurity 75 (CAS CATO-C4X-291575)
- Benzyl-PEG2-CH2COOH (CAS 91842-53-4)
- tert-Butyl 4-(5,5-dimethyl-2-oxo-1,3-oxazinan-3-yl)piperidine-1-carboxylate (CAS 1215596-09-0)
- C-Peptide（dog） (CAS 39016-05-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com