Letermovir Impurity 75 CAS CATO-C4X-291575
| CAS No. | CATO-C4X-291575 |
| Molecular Formula | C19H16F4N2O4 |
| Molecular Weight | 412.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Letermovir Impurity 75 (CAS CATO-C4X-291575), a pharmacopoeial impurity reference standard (molecular formula C19H16F4N2O4, MW 412.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Letermovir Impurity 75 (C19H16F4N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 412.33 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16F4N2O4 |
| Molecular Weight | 412.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Letermovir Standards
- Letermovir Impurity 132 (CAS CATO-C4X-2915132)
- Letermovir Impurity 71 (CAS CATO-C4X-291571)
- Letermovir Impurity 83 (CAS CATO-C4X-291583)
- Letermovir Impurity 85 (CAS CATO-C4X-291585)
- Letermovir Impurity 90 (CAS CATO-C4X-291590)
- Letermovir Impurity 92 (CAS CATO-C4X-291592)
- Letermovir Impurity 93 (CAS CATO-C4X-291593)
- Letermovir impurity 137 (CAS CATO-C4X-2915137)
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