2-((5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide CAS 499103-76-3
| CAS No. | 499103-76-3 |
| Molecular Formula | C19H16F3N3O2S3 |
| Molecular Weight | 471.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide.
2-((5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 499103-76-3), molecular formula C19H16F3N3O2S3 and molecular weight 471.54 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-((5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 471.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16F3N3O2S3 |
| Molecular Weight | 471.54 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 3 |
Related Methoxybenzyl Standards
- 3-(Bis(4-methoxybenzyl)amino)-6-bromo-2-fluoro-5-methylbenzaldehyde (CAS 2706637-93-4)
- N-(4-methoxybenzyl)-2-((3-methyl-4-oxo-7-(p-tolyl)-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040675-46-4)
- 1-(4-Methoxybenzyl)-3-(((4-methoxybenzyl)oxy)methyl)-5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2489244-20-2)
- 2-((3-Methoxybenzyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477331-25-2)
- 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile (CAS 1144853-59-7)
- 3-(Bis(4-methoxybenzyl)amino)-2-fluoro-5-methyl-6-(trifluoromethyl)benzaldehyde (CAS 2706637-94-5)
- 2-((5-((4-Methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(4-sulfamoylphenyl)acetamide (CAS 499103-73-0)
- N-(1-((2-methoxybenzyl)amino)-1-oxopropan-2-yl)-1-(phenylsulfonyl)piperidine-4-carboxamide (CAS 2197231-02-8)
Recommended Standards
- 1-Amino-4-hydroxy-2-(4-(octyloxy)benzoyl)anthracene-9,10-dione (CAS 89868-46-2)
- 2-[2-(3-Diethylamino-1-oxo-1H-benzo[f]chromen-2-yl)-vinyl]-6-methoxy-benzoic acid methyl ester (CAS 365542-82-1)
- {3-[(Benzylthio)methyl]phenyl}{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}methanone (CAS 260781-45-1)
- Ethyl 5-(2,4-bis(benzyloxy)-5-isopropylphenyl)isoxazole-3-carboxylate (CAS 747414-20-6)
- Defluoro Flumazenil Isothiocyanate (CAS 954107-48-3)
- 2-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-amine dihydrobromide (CAS 250258-74-3)
- Methyl 3-(2,4-dimethoxyphenyl)-1H-pyrazole-5-carboxylate (CAS 890624-62-1)
- [(2,4-dichlorophenyl)(pyridin-3-yl)methyl](ethyl)amine (CAS 1304390-10-0)
- 5-Bromo-2-((3-(trifluoromethyl)benzyl)oxy)benzaldehyde (CAS 590360-00-2)
- Azathioprine EP Impurity D (CAS 6339-54-4)
- Diacerein (CAS 13739-02-1)
- 5-Acetyl-6-methoxynicotinonitrile (CAS 1256789-08-8)
- 2-(5-Ethyl-2-methoxyphenyl)-4-methylpyrrolidine (CAS 603068-65-1)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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